Font C, Bradbury M W, Strong A J, Plagaro-Cordero M E
Rev Esp Fisiol. 1985 Jun;41(2):171-6.
Studies on the permeability of potassium at the blood-brain barrier of rats show that, under normal conditions, the concentration of this ion is kept constant although wide variations in plasma are present. 86Rb has been utilized as an analog of K+. The permeability constant for control animals (arterial blood pressure of 100 +/- 3 mmHg), has been determined in 0.926 +/- 0.02 ml X g-1 X h-1 (brain cortex), and 1.107 +/- 0.12 ml X g-1 X h-1 (cerebellum). The permeability constant for hypotensive animals (arterial blood pressure of 40 +/- 5 mmHg), has been determined in 0.473 +/- 0.03 ml X g-1 X h-1 (brain cortex), and 0.608 +/- 0.06 ml X g-1 X h-1 (cerebellum). During hypotension there is a marked decrease in the permeability constant of 86Rb at the blood-brain barrier of rats.
对大鼠血脑屏障处钾通透性的研究表明，在正常情况下，尽管血浆中钾离子浓度存在很大变化，但该离子的浓度仍保持恒定。86Rb已被用作K+的类似物。对照动物（动脉血压为100±3 mmHg）的通透性常数在脑皮质为0.926±0.02 ml·g-1·h-1，在小脑为1.107±0.12 ml·g-1·h-1。低血压动物（动脉血压为40±5 mmHg）的通透性常数在脑皮质为0.473±0.03 ml·g-1·h-1，在小脑为0.608±0.06 ml·g-1·h-1。在低血压期间，大鼠血脑屏障处86Rb的通透性常数显著降低。
