Zhang Longxiang, Tuoliken Haishaer, Li Jian, Gao Hongliang
The Second Department of Gastroenterology, the First Affiliated Hospital of Xinjiang, Medical University, Urumqi, 830000 Xinjiang China.
Food Sci Biotechnol. 2024 Nov 25;34(10):2087-2099. doi: 10.1007/s10068-024-01759-x. eCollection 2025 Jun.
The relationship between diet and human physical and mental health is highly interconnected and has been significantly correlated with the occurrence of various diseases, including neurological disorders, cancer, and chronic inflammatory diseases. Moreover, diet has been demonstrated to play a pivotal role in governing gut microbiota composition, making it one of the most influential factors. The diet is crucial in connecting humans and their gut microorganisms. The nutrients ingested supply energy to the body and serve as substrates for the metabolic processes of the gut microorganisms. Consequently, the gut flora and their metabolites reciprocally impact the host's metabolism, thereby influencing the physiological state of the human body. Extensive investigations on human and mouse models have revealed that diet potentially underlies various effects on human health and disease.
饮食与人类身心健康之间的关系高度相互关联，并且与包括神经紊乱、癌症和慢性炎症性疾病在内的各种疾病的发生显著相关。此外，饮食已被证明在控制肠道微生物群组成方面起着关键作用，使其成为最具影响力的因素之一。饮食在连接人类及其肠道微生物方面至关重要。摄入的营养物质为身体提供能量，并作为肠道微生物代谢过程的底物。因此，肠道菌群及其代谢产物相互影响宿主的新陈代谢，从而影响人体的生理状态。对人类和小鼠模型的广泛研究表明，饮食可能是影响人类健康和疾病的各种效应的潜在基础。
