Sameer Saad, Qassim Aya J, Aqel Ali, Al-Asa'd Yousef H, Thappy Shaefiq Babu
Internal Medicine, Hamad General Hospital, Doha, QAT.
Nephrology, Hamad General Hospital, Doha, QAT.
Cureus. 2025 Apr 11;17(4):e82069. doi: 10.7759/cureus.82069. eCollection 2025 Apr.
Hyperaldosteronism often clinically manifests as hypertension with mild to moderate hypokalemia. However, in rare cases, it can also present primarily with severe hypokalemia. In this case report, we will be discussing our patient, a 43-year-old woman who presented with abdominal cramps and vomiting, along with severe muscle cramps resulting in an inability to walk. She was found to have an undetectable level of serum potassium and prolonged QT interval on her ECG. After aggressive electrolyte correction and further imaging and endocrinology studies, she was diagnosed to have primary hyperaldosteronism. She was appropriately referred for urgent outpatient adrenalectomy, which turned out to be curative. Our case highlights the importance of timely diagnosis, interventions, and multidisciplinary care for patients with primary hyperaldosteronism.
原发性醛固酮增多症临床上常表现为高血压伴轻度至中度低钾血症。然而,在罕见情况下,它也可能主要表现为严重低钾血症。在本病例报告中,我们将讨论我们的患者,一名43岁女性,她出现腹部绞痛和呕吐,伴有严重的肌肉痉挛,导致无法行走。她的血清钾水平检测不到,心电图显示QT间期延长。经过积极的电解质纠正以及进一步的影像学和内分泌学检查,她被诊断为原发性醛固酮增多症。她被及时转诊进行紧急门诊肾上腺切除术,结果证明手术治愈了她的疾病。我们的病例强调了对原发性醛固酮增多症患者进行及时诊断、干预和多学科护理的重要性。