Mohammadi Mohammad, Bazrafshan Drissi Hamed, Rahmanian Mahdi, Kojuri Javad, Attar Armin, Safari Ali, Bazrafshan Mehdi, Izadpanah Peyman
Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IRN.
Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, IRN.
Cureus. 2025 Apr 8;17(4):e81924. doi: 10.7759/cureus.81924. eCollection 2025 Apr.
Chronic coronary syndrome (CCS) is a common disease worldwide. Advances in technology, including quantitative coronary angiography, have improved CCS management. In the present study, we aim to investigate the correlation and agreement between intravascular ultrasound minimum luminal area (IVUSMLA) and quantitative minimum luminal area (QMLA) in CCS patients with intermediate coronary lesions.
Data from CCS patients with at least one-vessel coronary occlusion from March 2022 to March 2023 were collected. Gathered data included patients' age, gender, QMLA, IVUSMLA, and patients' previous medical history, including hypertension, diabetes, and smoking. The target lesion in this study was intermediate (50% to 70%) stenosis. Agreement between IVUSMLA and QMLA was assessed using the Bland-Altman plot. A p-value (p) of less than 0.05 was considered statistically significant. R version 4.4.1 software (R Foundation for Statistical Computing, Vienna, Austria) was used for data analysis.
This study included 52 (59.1%) men and 36 (40.9%) women with a mean age of 67.15 ± 10.63 and 64 ± 12.61 (p = 0.533), respectively. The mean for IVUSMLA and QMLA was 2.80 ± 1.54 and 2.6 ± 1.57, respectively. QMLA was highly correlated with IVUSMLA (r = 0.997; p <0.001). Both QMLA and IVUSMLA had moderately good agreement, presenting with small mean difference values but large values of root mean squared deviation (IVUSMLA - QMLA = 0.13 ± 0.11).
IVUSMLA and QMLA are highly correlated to each other and have good agreement. So, QMLA can be used instead of IVUSMLA in intermediate coronary lesions.
慢性冠状动脉综合征（CCS）是一种全球常见疾病。包括定量冠状动脉造影在内的技术进步改善了CCS的管理。在本研究中，我们旨在调查中度冠状动脉病变的CCS患者血管内超声最小管腔面积（IVUSMLA）与定量最小管腔面积（QMLA）之间的相关性和一致性。
收集2022年3月至2023年3月至少有一处血管冠状动脉闭塞的CCS患者的数据。收集的数据包括患者的年龄、性别、QMLA、IVUSMLA以及患者既往病史，包括高血压、糖尿病和吸烟情况。本研究中的目标病变为中度（50%至70%）狭窄。使用布兰德-奥特曼图评估IVUSMLA与QMLA之间的一致性。p值小于0.05被认为具有统计学意义。使用R版本4.4.1软件（奥地利维也纳的R统计计算基金会）进行数据分析。
本研究纳入52名（59.1%）男性和36名（40.9%）女性，平均年龄分别为67.15±10.63岁和64±12.61岁（p = 0.533）。IVUSMLA和QMLA的平均值分别为2.80±1.54和2.6±1.57。QMLA与IVUSMLA高度相关（r = 0.997；p <0.001）。QMLA和IVUSMLA均具有中等程度的良好一致性，平均差值较小，但均方根偏差值较大（IVUSMLA - QMLA = 0.13±0.11）。
IVUSMLA与QMLA高度相关且具有良好的一致性。因此，在中度冠状动脉病变中，QMLA可替代IVUSMLA使用。
