Adhyatma Kharisma Prasetya, Warli Muhammad Haritsyah, Khosasi Felix, Harahap Dianita Halimah
Department of Urology, Division of Urology, Faculty of Medicine, Haji Adam Malik General Hospital, University of North Sumatra, Medan, Indonesia.
Division of Urology, Department of Surgery, Faculty of Medicine Universitas Sumatera Utara, Adam Malik Hospital, Medan, Indonesia.
Urol Ann. 2025 Apr-Jun;17(2):97-107. doi: 10.4103/ua.ua_99_24. Epub 2025 Apr 17.
Ureteral stents are crucial in urological surgery, promoting urine passage and preventing obstruction. They have undergone design, material, and covering changes to minimize pain and enhance efficiency. Researchers are exploring the use of magnetic stents, which use magnets attached to the stent's end.
This research aims to evaluate and analyze the expulsion of magnetic double J (DJ) stents as compared to conventional methods DJ stents, using qualitative and quantitative data from the literature about morbidity, discomfort, cost, duration, safety, and efficiency.
This research is a systematic review and meta-analysis of randomized controlled trials (RCTs).
RCTs comparing the removal of magnetic DJ stents to conventional stents were identified through an extensive search Scopus, Web of Science, PubMed, and Cochrane from January 2014 to January 2024. The search methodology and criteria for eligibility were developed using a modified PICO framework, and the risk of bias in the RCTs was evaluated with the RoB-2 tool. The removal duration, ureteral stent symptom questionnaire (USSQ), and pain (measured by visual analog scale) were pooled for meta-analysis.
The Cochrane Collaboration tool called Review Manager 5.4 will be used to collect quantitative data. The main outcome was evaluated using continuous data, with the mean difference (MD) and a 95% confidence interval (CI) applied. A < 0.05 was deemed statistically significant. Heterogeneity between studies will be evaluated in this meta-analysis using ² (²; Inconsistency).
There were six RCT studies involving 570 participants that were finally eligible for the quantitative analysis. Magnetic DJ stent was found to significantly shorten the duration of removal (MD -30.51; 95% CI, -51.82--9.21; = 0.005) and less pain during removal (MD -2.71; 95% CI, -3.74--1.68; < 0.00001) than conventional DJ stent. USSQ scores for urinary symptoms (MD 1.88; 95% CI, 0.56-3.19; = 0.005) and sexual matters (MD 1.18; 95% CI, 0.54-1.82; = 0.0003) were significantly higher for magnetic than for conventional stents.
Magnetic DJ stent removal offers enhanced safety, efficiency, less pain, a shorter time of removal, and lower costs compared to conventional methods. However, it has a higher UUSQ score for urinary symptoms and sexual matters.
输尿管支架在泌尿外科手术中至关重要,可促进尿液排出并防止梗阻。它们在设计、材料和涂层方面都有改进,以尽量减少疼痛并提高效率。研究人员正在探索使用磁性支架,即在支架末端附着磁体。
本研究旨在利用文献中关于发病率、不适、成本、持续时间、安全性和效率的定性和定量数据,评估和分析磁性双J(DJ)支架与传统DJ支架相比的排出情况。
本研究是一项对随机对照试验(RCT)的系统评价和荟萃分析。
通过对Scopus、科学网、PubMed和Cochrane数据库进行广泛检索,确定了2014年1月至2024年1月期间比较磁性DJ支架取出与传统支架取出的RCT。使用改良的PICO框架制定检索方法和纳入标准,并使用RoB - 2工具评估RCT中的偏倚风险。将取出持续时间、输尿管支架症状问卷(USSQ)和疼痛(通过视觉模拟量表测量)汇总进行荟萃分析。
将使用名为Review Manager 5.4的Cochrane协作工具收集定量数据。主要结局使用连续数据进行评估,应用平均差(MD)和95%置信区间(CI)。P < 0.05被认为具有统计学意义。本荟萃分析将使用I²(I²;不一致性)评估研究间的异质性。
最终有6项涉及570名参与者的RCT研究符合定量分析要求。结果发现,与传统DJ支架相比,磁性DJ支架显著缩短了取出持续时间(MD -30.51;95% CI,-51.82至-9.21;P = 0.005),且取出过程中疼痛较轻(MD -2.71;95% CI,-3.74至-1.68;P < 0.00001)。磁性支架的尿液症状USSQ评分(MD 1.88;95% CI,0.56至3.19;P = 0.005)和性相关问题评分(MD 1.18;95% CI,0.54至1.82;P = 0.0003)显著高于传统支架。
与传统方法相比,磁性DJ支架取出具有更高的安全性、效率,疼痛更少,取出时间更短且成本更低。然而,其尿液症状和性相关问题的USSQ评分较高。