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[视网膜静脉阻塞中的血液流变学变化]

[Hemorheological changes in retinal vein occlusions].

作者信息

Peduzzi M, Debbia A, Guerrieri F, Zirilli E, Bolzani R, Barbieri U

出版信息

Ric Clin Lab. 1985;15 Suppl 1:321-6.

PMID:4035223
Abstract

Some hemorheological factors were studied in 34 patients affected by retinal vein occlusion (RVO) and in 25 healthy control subjects. Whole blood viscosity, plasma viscosity, fibrinogen and hematocrit were increased in RVO patients compared with controls. Erythrocyte filterability was reduced in RVO patients compared with controls. However, when evaluating the type of capillaropathy at fluorescein angiography, blood viscosity and plasma viscosity were altered both in patients with and without evidence of capillary non-perfusion. Reduction of red cell filterability showed statistical significance only in patients with capillary non-perfusion. This finding suggests that reduced erythrocyte filterability might be a causal factor in the development of capillary non-perfusion in RVO patients.

摘要

对34例视网膜静脉阻塞(RVO)患者和25名健康对照者的一些血液流变学因素进行了研究。与对照组相比,RVO患者的全血粘度、血浆粘度、纤维蛋白原和血细胞比容均升高。与对照组相比,RVO患者的红细胞滤过率降低。然而,在荧光血管造影评估毛细血管病变类型时,有和没有毛细血管无灌注证据的患者的血液粘度和血浆粘度均发生了改变。红细胞滤过率降低仅在有毛细血管无灌注的患者中具有统计学意义。这一发现表明,红细胞滤过率降低可能是RVO患者毛细血管无灌注发生的一个因果因素。

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