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整体大于部分之和:在一所三级军事医院的抗菌药物管理计划中实施抗菌药物管理咨询服务对抗生素使用的影响

The whole is greater than the sum of its parts: effect of implementing an ABS consultation service in the ABS program on antibiotic consumption at a tertiary military hospital.

作者信息

Zeidler David, Scheumann Gwendolyn, Baessler Claudia, Döhla Manuel, Preuß Dominic, Rauschning Dominic

机构信息

Department of Pharmacy, Bundeswehr Central Hospital Koblenz, Germany.

Department IB of Internal Medicine, Division of Infectious Diseases, Bundeswehr Central Hospital Koblenz, Germany.

出版信息

GMS Hyg Infect Control. 2025 Mar 10;20:Doc11. doi: 10.3205/dgkh000540. eCollection 2025.

Abstract

BACKGROUND

Infections with multidrug resistant (MDR) pathogens represent an enormous challenge for the healthcare system. By implementing the principles of Antibiotic Stewardship (ABS), the rational use of antibiotics is promoted to counteract the increasing development of resistance on the one hand and to ensure adequate treatment for patients on the other.

METHODS

An interdisciplinary ABS team has therefore been set up at the Bundeswehr Central Hospital and is available to medical staff every working day as part of a consultation and ward-rounds service. The work of the ABS team primarily serves to advise on the treatment, diagnosis and prevention of infectious diseases. It also intends to provide knowledge during the training of young medical officers in order to promote the rational use of antibiotics even outside the Bundeswehr Central Hospital.

RESULTS

Since the implementation of the consultation and ward-rounds service, antibiotic consumption at the Bundeswehr Central Hospital has been reduced by 25%. In this context, the halving of carbapenem consumption is particularly noteworthy. Furthermore, the rising number of consultation requests shows an increasing need for the service and acts as a marker for ABS awareness.

CONCLUSION

The reduction in antibiotic consumption is not solely due to the mentioned service, but is also the result of interdisciplinary ABS measures.

摘要

背景

耐多药(MDR)病原体感染给医疗系统带来了巨大挑战。通过实施抗生素管理(ABS)原则,一方面促进抗生素的合理使用,以应对耐药性不断增加的问题,另一方面确保为患者提供充分的治疗。

方法

因此,德国联邦国防军中央医院成立了一个跨学科的ABS团队,作为咨询和查房服务的一部分,在每个工作日为医务人员提供服务。ABS团队的工作主要是就传染病的治疗、诊断和预防提供建议。它还打算在年轻医务人员的培训过程中提供知识,以便即使在德国联邦国防军中央医院之外也能促进抗生素的合理使用。

结果

自实施咨询和查房服务以来,德国联邦国防军中央医院的抗生素消耗量减少了25%。在此背景下,碳青霉烯类药物消耗量减半尤其值得注意。此外,咨询请求数量的增加表明对该服务的需求不断增加,并成为ABS意识的一个标志。

结论

抗生素消耗量的减少不仅归因于上述服务,也是跨学科ABS措施的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dce/12060362/bf08bf01193a/HIC-20-11-g-001.jpg

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