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G组链球菌性咽炎后急性非风湿性心肌炎:一名年轻成年人中急性心肌缺血的罕见模仿病例

Acute Non-Rheumatic Myocarditis Following Group G Streptococcal Pharyngitis: A Rare Mimic of Acute Myocardial Ischemia in a Young Adult.

作者信息

Rimsky Elizabeth R, Jia Kaiyu, Sattarzadeh Aysan, Loeffler Jeffrey, Grabie Yisroel, Spagnola Jonathan

机构信息

Department of Medicine, Northwell at Staten Island University Hospital, Staten Island, USA.

Department of Cardiology, Northwell at Staten Island University Hospital, Staten Island, USA.

出版信息

Eur J Case Rep Intern Med. 2025 Apr 23;12(5):005354. doi: 10.12890/2025_005354. eCollection 2025.

Abstract

BACKGROUND

Acute myocarditis is a rare but serious inflammatory condition of the myocardium, often triggered by infections or rheumatic heart disease. While group A is commonly associated with bacterial myocarditis, group G is rarely implicated. This case highlights a rare instance of non-rheumatic acute myocarditis also known as Streptococcal pharyngitis acute myocarditis caused by group G in a 19-year-old male without rheumatic fever.

CASE REPORT

A previously healthy 19-year-old male presented with chest pain, fever, and sore throat, prompting hospitalization. The diagnosis of acute myocarditis was based on elevated cardiac biomarkers, electrocardiographic abnormalities, and cardiac magnetic resonance imaging, with group G infection confirmed by throat polymerase chain reaction. The patient responded well to antibiotics and anti-inflammatory therapy.

CONCLUSIONS

This case highlights group G -induced pharyngitis acute myocarditis, stressing the need for prompt diagnosis and treatment in young adults presenting with recent streptococcal pharyngitis.

LEARNING POINTS

This case highlights a rare instance of non-rheumatic acute myocarditis also known as Streptococcal pharyngitis acute myocarditis, caused by group G streptococcus in a 19-year-old male without rheumatic fever.Streptococcal pharyngitis acute myocarditis may present with clinical features closely resembling an acute coronary syndrome; hence advance cardiac imaging is essential to confirm myocarditis and rule out true ischemic heart disease.Cardiac magnetic resonance imaging was used to diagnose Streptococcal pharyngitis acute myocarditis which showed subepicardial hyper-enhancement 4 weeks after discharge and resolution of symptoms.Prompt diagnosis was achieved, and the patient was treated with antibiotics and anti-inflammatory therapy in a timely fashion with good response.

摘要

背景

急性心肌炎是一种罕见但严重的心肌炎症性疾病,常由感染或风湿性心脏病引发。虽然A组通常与细菌性心肌炎相关,但G组很少涉及。本病例突出了一例罕见的非风湿性急性心肌炎,也称为由G组链球菌引起的链球菌性咽炎急性心肌炎,发生在一名无风湿热的19岁男性身上。

病例报告

一名此前健康的19岁男性因胸痛、发热和喉咙痛入院。急性心肌炎的诊断基于心脏生物标志物升高、心电图异常和心脏磁共振成像,咽喉聚合酶链反应证实为G组感染。患者对抗生素和抗炎治疗反应良好。

结论

本病例突出了G组引起的咽炎急性心肌炎,强调了对近期患有链球菌性咽炎的年轻人进行及时诊断和治疗的必要性。

学习要点

本病例突出了一例罕见的非风湿性急性心肌炎,也称为链球菌性咽炎急性心肌炎,由G组链球菌引起,发生在一名无风湿热的19岁男性身上。链球菌性咽炎急性心肌炎可能表现出与急性冠状动脉综合征极为相似的临床特征;因此,先进的心脏成像对于确诊心肌炎和排除真正的缺血性心脏病至关重要。心脏磁共振成像用于诊断链球菌性咽炎急性心肌炎,其显示出院4周后心外膜下强化增强以及症状缓解。实现了及时诊断,患者及时接受了抗生素和抗炎治疗,反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78e4/12061197/a9ba380bf768/5354_Fig1.jpg

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