Maroto-Rodríguez Raquel, Tibau-Alberdi María, Font Bilbeny Mercè, Paz Ramírez Guillem, Gómez Blanco Maria Fernanda, Pérez Prieto Andrés, Barrera Veloza Paola, Picallo Fernández Miguel, Chicaiza García Tania
Consorci Sanitari del Maresme, Barcelona, Spain.
Hand (N Y). 2025 May 12:15589447251339503. doi: 10.1177/15589447251339503.
Dupuytren disease is a progressive fibrotic condition of the hand that often leads to contractures. Although its etiology remains multifactorial, recent studies suggest potential associations with surgical interventions for carpal tunnel syndrome (CTS) and trigger finger (TF). Understanding the incidence and risk factors for Dupuytren disease development following these procedures may improve postoperative management and early detection.
A retrospective study was conducted on 426 patients who underwent surgical treatment for CTS or TF. The incidence of Dupuytren disease development postsurgery was assessed, and data on demographics, comorbidities, occupational factors, and type of surgery were collected. Statistical analysis, including odds ratio (OR) calculations, was used to identify risk factors associated with Dupuytren disease onset.
Seven percent of the study population developed new-onset Dupuytren disease within an average of 15.2 weeks postsurgery, with most cases presenting as early-stage nodule formation. The fourth digit was most commonly affected (73.3%). Significant associations were observed between Dupuytren disease onset and comorbidities, such as rheumatoid arthritis (OR = 3.24) and shoulder capsulitis (OR = 9.7), as well as occupational factors like manual labor and vibration exposure (OR = 2.45). Patients treated for TF had a 2.3-fold higher risk of developing Dupuytren disease compared with those treated for CTS.
The findings highlight the potential for Dupuytren disease development following CTS and TF surgeries, emphasizing the need for proactive monitoring of at-risk patients. Further research is warranted to explore underlying mechanisms and optimize preventive and management strategies for this patient population.
杜普伊特伦挛缩病是一种手部进行性纤维化疾病，常导致挛缩。尽管其病因仍是多因素的，但最近的研究表明，它可能与腕管综合征（CTS）和扳机指（TF）的手术干预有关。了解这些手术后杜普伊特伦挛缩病发生的发病率和危险因素，可能会改善术后管理和早期检测。
对426例行CTS或TF手术治疗的患者进行了一项回顾性研究。评估术后杜普伊特伦挛缩病发生的发病率，并收集有关人口统计学、合并症、职业因素和手术类型的数据。采用包括比值比（OR）计算在内的统计分析方法，以确定与杜普伊特伦挛缩病发病相关的危险因素。
7%的研究人群在术后平均15.2周内出现新发杜普伊特伦挛缩病，大多数病例表现为早期结节形成。第四指最常受累（73.3%）。观察到杜普伊特伦挛缩病发病与合并症（如类风湿性关节炎，OR = 3.24；肩周炎，OR = 9.7）以及体力劳动和振动暴露等职业因素（OR = 2.45）之间存在显著关联。与接受CTS治疗的患者相比，接受TF治疗的患者发生杜普伊特伦挛缩病的风险高2.3倍。
研究结果突出了CTS和TF手术后发生杜普伊特伦挛缩病的可能性，强调了对高危患者进行积极监测的必要性。有必要进一步研究以探索潜在机制，并优化针对该患者群体的预防和管理策略。
