McCormack G D, Barth W F
Semin Arthritis Rheum. 1985 Aug;15(1):73-9. doi: 10.1016/0049-0172(85)90012-5.
Five patients with a lupus-like syndrome secondary to quinidine are described. Eleven other cases have previously been reported. The quinidine induced lupus syndrome is similar to that seen with procainamide and hydralazine treatment but occurs less frequently. The lower incidence may reflect a difference in the metabolism of quinidine. Quinidine should be considered as potentially responsible when multisystem disease appears in patients receiving this drug.
本文描述了5例因奎尼丁引发狼疮样综合征的患者。此前已有另外11例相关病例的报道。奎尼丁诱发的狼疮综合征与使用普鲁卡因胺和肼苯哒嗪治疗时出现的情况相似,但发病率较低。较低的发病率可能反映了奎尼丁代谢的差异。当接受该药治疗的患者出现多系统疾病时,应考虑奎尼丁可能是病因。