精准的前景：探索瑞马唑仑在小儿麻醉中的作用
The promise of precision: exploring the role of remimazolam in paediatric anaesthesia.
作者信息
Hansen Tom Giedsing, Engelhardt Thomas
机构信息
Department of Anaesthesiology & Intensive Care, Akershus University Hospital, Lørenskog, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Pediatric Anesthesia, Montreal Children's Hospital, Montreal, QC, Canada; Department of Anesthesia, McGill University, Montreal, QC, Canada.
出版信息
Br J Anaesth. 2025 Jun;134(6):1613-1615. doi: 10.1016/j.bja.2025.03.010. Epub 2025 Apr 17.
Remimazolam represents a breakthrough in paediatric anaesthesia, with predictable pharmacokinetics and safety profile. A recent study provides key dosing data for children while noting the need for comparative trials, pharmacogenetic studies, and long-term safety evaluations. We highlight its potential for broad clinical use, but call for further research to optimise its integration into paediatric anaesthesia practice.
瑞米唑仑是小儿麻醉领域的一项突破，具有可预测的药代动力学和安全性。一项近期研究提供了儿童的关键给药数据，同时指出需要进行对比试验、药物遗传学研究和长期安全性评估。我们强调其广泛临床应用的潜力，但呼吁开展进一步研究，以优化其在小儿麻醉实践中的应用。
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