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Achieving the fast track 90-90-90 and 95-95-95 targets in sub-Saharan Africa: A rapid review.

作者信息

Nxumalo Celenkosini T, Buthelezi Usangiphile, Chiya Hlolisile, Makgobole Mokgadi U, Mpofana Nomakhosi, Mgwaba Themba, Luvuno Zamasomi

机构信息

Department of Research Development and Postgraduate Support, Office of the DVC Research and Innovation, University of the Western Cape, Cape Town, South Africa.

Centre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

出版信息

J Public Health Afr. 2025 Apr 21;16(1):691. doi: 10.4102/jphia.v16i1.691. eCollection 2025.


DOI:10.4102/jphia.v16i1.691
PMID:40356732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12067493/
Abstract

BACKGROUND: The Joint United Nations Programme on HIV/AIDS (UNAIDS) set targets for 95% of people living with human immunodeficiency virus (HIV) infection to know their status, 95% to receive antiretroviral therapy (ART) and 95% to achieve viral suppression. These targets mirror the 90-90-90 targets that were aimed to be met by 2020 to end AIDS as a public health threat by 2030. AIM: The study aims to synthesise evidence on recommendations, best practices and challenges in achieving 90-90-90 escalated to 95-95-95 fast-track targets in sub-Saharan Africa. SETTING: The review included empirical evidence from sub-Saharan Africa. METHOD: We followed Arksey and O'Malley's methodological framework for this scoping review. A systematic search of relevant articles was conducted using electronic databases such as Scopus, EBSCOHost, PubMed, Science Direct and Sabinet. The results were reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram. RESULTS: There were 6943 relevant study titles that were identified from the five databases. Following duplicates removal, title and abstract screening, 31 articles were included for full-text review. A combination of qualitative, quantitative and mixed methods studies were included. CONCLUSION: The 90-90-90 targets have been achieved in part, but challenges remain, particularly for key and vulnerable populations. Even as successes and challenges towards '90-90-90 by 2020' are outlined, new fast-track '95-95-95 by 2030' targets have been established because of concerns that the original targets may not have achieved epidemic control. CONTRIBUTION: The findings of this review have implications for policy and practice related to interventions to facilitate the realisation of HIV epidemic control as outlined by the UNAIDS 95-95-95 treatment cascade.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6eb/12067493/4b34b613e92b/JPHIA-16-691-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6eb/12067493/4b34b613e92b/JPHIA-16-691-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6eb/12067493/4b34b613e92b/JPHIA-16-691-g001.jpg

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本文引用的文献

[1]
Left behind on the path to 90-90-90: understanding and responding to HIV among displaced people.

J Int AIDS Soc. 2022-11

[2]
Socioeconomic inequalities in the 90-90-90 target, among people living with HIV in 12 sub-Saharan African countries - Implications for achieving the 95-95-95 target - Analysis of population-based surveys.

EClinicalMedicine. 2022-9-17

[3]
Reaching 95-95-95 targets: The role of private sector health facilities in closing the HIV detection gap-Kisumu Kenya, 2018.

Int J STD AIDS. 2022-4

[4]
Unsuppressed viral load after intensive adherence counselling in rural eastern Uganda; a case of Kamuli district, Uganda.

BMC Public Health. 2021-12-18

[5]
To achieve 95-95-95 targets we must reach men and youth: High level of knowledge of HIV status, ART coverage, and viral suppression in the Botswana Combination Prevention Project through universal test and treat approach.

PLoS One. 2021

[6]
Progress Toward the 90-90-90 HIV Targets in Zimbabwe and Identifying Those Left Behind.

J Acquir Immune Defic Syndr. 2021-11-1

[7]
Understating the barriers to achievement of the UNAIDS 90-90-90 goal in Tanzania using a population-based HIV impact assessment survey 2016-2017.

AIDS Care. 2022-6

[8]
Determinants of gender disparities in scaling up the first 90 towards the UNAIDS 90-90-90 targets in South Africa: findings from the 2017 household-based national cross-sectional survey.

AIDS Res Ther. 2021-4-28

[9]
Not yet 90-90-90: A quality improvement approach to human immunodeficiency virus viral suppression in paediatric patients in the rural Eastern Cape, South Africa.

S Afr Fam Pract (2004). 2020-10-15

[10]
Towards achieving the 90-90-90 HIV targets: results from the south African 2017 national HIV survey.

BMC Public Health. 2020-9-9

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