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提升南非艾滋病规划署 90-90-90 目标前 90 倡议的性别差距的决定因素:来自 2017 年基于家庭的全国横断面调查的结果。

Determinants of gender disparities in scaling up the first 90 towards the UNAIDS 90-90-90 targets in South Africa: findings from the 2017 household-based national cross-sectional survey.

机构信息

Human and Social Capabilities Research Division, Human Sciences Research Council, 118 Buitengracht St, Cape Town City Centre, Cape Town, 8000, South Africa.

School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

出版信息

AIDS Res Ther. 2021 Apr 28;18(1):24. doi: 10.1186/s12981-021-00346-y.

Abstract

BACKGROUND

The first 90 of UNAIDS 90-90-90 targets to have 90% of the people living with HIV know their status is an important entry point to the HIV treatment cascade and care continuum, but evidence shows that there is a large gap between males and females in this regard. It is therefore important to understand barriers and facilitators of achieving the first 90 target. This study examined determinants of the first 90 target among females and males in order to inform strategies aimed at improving the HIV cascade in South Africa.

METHODS

The data used in the analysis were obtained from a 2017 household-based cross-sectional nationally representative survey conducted using a multi-stage stratified cluster random sampling design. A series of hierarchical multiple logistic regression models were fitted to identify the determinants of the first 90 target by gender.

RESULTS

Overall, 84.8% of HIV-positive individuals aged 15 years and older were aware of their HIV status. Females were significantly more aware of their HIV status compared to males (88.7% vs 78.2%, p < 0.001). Both females aged 25 to 49 years [aOR = 3.20 (95% CI 1.35-7.57), p = 0.008], and 50 years and older [aOR = 3.19 (95% CI 1.04-9.76), p = 0.042] and males aged 25 to 49 years [aOR = 3.00 (95% CI 1.13-7.97), p = 0.028], and 50 years and older [aOR = 7.25 (95% CI 2.07-25.36), p = 0.002] were significantly more likely to know their HIV status compared to those aged 15 to 19 years. Males with tertiary education level were significantly more likely to be aware of their HIV positive status [aOR = 75.24 (95% CI 9.07-624.26), p < 0.001] compared to those with no education or with primary level education. Females with secondary [aOR = 3.28 (95% CI 1.20-8.99), p = 0.021] and matric [aOR = 4.35 (95% CI 1.54-12.37), p = 0.006] educational levels were significantly more likely to be aware of their HIV positive status, compared to those with no education or with primary level education.

CONCLUSION

Significant progress has been made with regards to reaching the UNAIDS first 90 target. In this context achieving the first 90 target is feasible but there is a need for additional interventions to reach the males especially youth including those with no education or low levels of education.

摘要

背景

联合国艾滋病规划署 90-90-90 目标的前 90 项是让 90%的艾滋病毒感染者了解自己的状况,这是艾滋病毒治疗连续体和关怀连续体的一个重要切入点,但有证据表明,男性和女性在这方面存在很大差距。因此,了解实现前 90 项目标的障碍和促进因素非常重要。本研究旨在探讨男女性实现前 90 项目标的决定因素,以便为改善南非的艾滋病毒连续体提供信息。

方法

分析中使用的数据来自于 2017 年使用多阶段分层聚类随机抽样设计进行的基于家庭的全国代表性横断面调查。采用一系列分层多逻辑回归模型,按性别确定实现前 90 项目标的决定因素。

结果

总体而言,84.8%的 15 岁及以上艾滋病毒阳性个体知晓自己的艾滋病毒状况。女性知晓自己艾滋病毒状况的比例明显高于男性(88.7%对 78.2%,p<0.001)。25 至 49 岁的女性(aOR=3.20,95%可信区间 1.35-7.57,p=0.008)和 50 岁及以上的女性(aOR=3.19,95%可信区间 1.04-9.76,p=0.042)和 25 至 49 岁的男性(aOR=3.00,95%可信区间 1.13-7.97,p=0.028)和 50 岁及以上的男性(aOR=7.25,95%可信区间 2.07-25.36,p=0.002),与 15 至 19 岁的男性相比,更有可能知晓自己的艾滋病毒状况。具有高等教育水平的男性与没有教育或只有小学教育水平的男性相比,更有可能知晓自己的艾滋病毒阳性状况(aOR=75.24,95%可信区间 9.07-624.26,p<0.001)。与没有教育或只有小学教育水平的女性相比,具有中学(aOR=3.28,95%可信区间 1.20-8.99,p=0.021)和预科(aOR=4.35,95%可信区间 1.54-12.37,p=0.006)教育水平的女性更有可能知晓自己的艾滋病毒阳性状况。

结论

在实现联合国艾滋病规划署的前 90 项目标方面取得了重大进展。在这种情况下,实现前 90 项目标是可行的,但需要采取额外的干预措施,以接触男性,特别是青年,包括那些没有受过教育或教育水平较低的人。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61c0/8080360/10349628a227/12981_2021_346_Fig1_HTML.jpg

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