Ye BaoLong, Chen ZiWen, Xie JunFeng, Xi KeXing, Zeng Xin, Zhong CaiLiang
Department of Gastrointestinal and Hernia Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, China.
Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Front Oncol. 2025 Apr 28;15:1512964. doi: 10.3389/fonc.2025.1512964. eCollection 2025.
Calcifying fibrous tumor (CFT) is an uncommon benign fibrous neoplastic lesion that may manifest as singular or multiple tumors and usually occurs in children or young adults. CFT originates in the muscularis propria of the stomach and is a very rare disease. Here, we report a case of gastric CFT with upper gastrointestinal bleeding.
A 39-year-old male was urgently referred to our hospital with haematemesis and melena that had developed over the course of 2 hours. Enhanced abdominal CT imaging revealed a nodular lesion, measuring approximately 3.2 × 2.1 × 1.6 cm, protruding from the posterior wall of the gastric body into the gastric lumen. The lesion exhibited scattered calcifications, smooth margins, and a CT attenuation value of 50 Hounsfield units (HU). Gastroscopic ultrasonography performed in the gastroenterology department revealed a semicircular submucosal mass with signs of active bleeding. Initially, the tumor was diagnosed as a gastrointestinal stromal tumor (GIST), and surgical intervention was undertaken due to ongoing hemorrhage. Postoperative histopathological examination confirmed the diagnosis of a gastric calcifying fibrous tumor (CFT).
CFT originating from the muscularis propria of the stomach is exceptionally rare, and the case presented here mimicked a gastric submucosal tumor (SMTs),clinicians should consider this differentia diagnosis when evaluating patients with suspected cases.
钙化性纤维瘤（CFT）是一种罕见的良性纤维性肿瘤性病变，可表现为单发或多发肿瘤，通常发生于儿童或年轻人。CFT起源于胃固有肌层，是一种非常罕见的疾病。在此，我们报告一例伴有上消化道出血的胃CFT病例。
一名39岁男性因在2小时内出现呕血和黑便而被紧急转诊至我院。腹部增强CT成像显示一个结节状病变，大小约为3.2×2.1×1.6 cm，从胃体后壁突出至胃腔内。该病变有散在钙化，边缘光滑，CT衰减值为50亨氏单位（HU）。消化内科进行的超声胃镜检查显示一个半圆形黏膜下肿块并有活动性出血迹象。最初，该肿瘤被诊断为胃肠道间质瘤（GIST），由于持续出血而进行了手术干预。术后组织病理学检查确诊为胃钙化性纤维瘤（CFT）。
起源于胃固有肌层的CFT极为罕见，本例病例类似胃黏膜下肿瘤（SMTs），临床医生在评估疑似病例患者时应考虑这种鉴别诊断。
