Padek Maggie, Butcher Rebecca, deLacerda Allen Rebecca, Surratt Hilary L, Subramain Maran, Tigges Beth, Eggleston Alyson G, Presley Jessica H, Matheson Trent, Sharareh Nasser
Frontiers Clinical and Translational Science Institute, University of Kansas Medical Center, Kansas City, KS, United States.
Dartmouth SYNERGY Clinical and Translational Science Institute, Geisel School of Medicine, Lebanon, NH, United States.
Front Public Health. 2025 Apr 28;13:1538494. doi: 10.3389/fpubh.2025.1538494. eCollection 2025.
Rural communities often lack access to healthcare, have limited resources and infrastructure, and may experience suboptimal translation of evidence-based interventions into practice or measurement of translational research impact. The Consortium of Rural States (CORES), comprising eight Clinical and Translational Science Award (CTSA) hubs, is a research consortium that focuses on clinical and translational research impacting rural health.
Utilizing the Translational Science Benefits Model (TSBM) framework, each CTSA hub's evaluation lead co-created an inventory of rural-focused activities, projects, and initiatives that occurred at their respective site during the funding period 2021-2023. Variables included program area; activity type and description; target population; activity status; outputs; and short-term outcomes. The evaluators then mapped site outcomes according to the four TSBM domains (clinical, community, economic, policy) and 30 subcategories (benefits).
184 rural-focused activities, projects and initiatives were identified across the hubs. All rural-focused efforts involved impacts in the Community and Clinical domains of the TSBM, with >60% focusing on Community impacts. These results suggest an opportunity gap to better define Economic and Policy-level impacts in the context of rural-focused initiatives.
This work demonstrates a novel mapping of the TSBM to rural health research settings and explores the nuances of using the concepts and domains of the TSBM as a coding tool. This work gives the Consortium insight on the types of projects and impacts that are supported and how to prioritize more exploration of the full range of translational science benefits in rural health initiatives going forward.
农村社区往往难以获得医疗保健服务，资源和基础设施有限，而且基于证据的干预措施在实际应用或转化研究影响评估方面可能效果欠佳。由八个临床与转化科学奖（CTSA）中心组成的农村州联盟（CORES）是一个专注于影响农村健康的临床与转化研究的研究联盟。
利用转化科学效益模型（TSBM）框架，每个CTSA中心的评估负责人共同创建了一份在2021年至2023年资助期内在各自地点开展的以农村为重点的活动、项目和倡议清单。变量包括项目领域；活动类型和描述；目标人群；活动状态；产出；以及短期成果。然后，评估人员根据TSBM的四个领域（临床、社区、经济、政策）和30个子类别（效益）对各中心的成果进行了映射。
在各中心共确定了184项以农村为重点的活动、项目和倡议。所有以农村为重点的工作都涉及TSBM的社区和临床领域的影响，其中超过60%的工作侧重于社区影响。这些结果表明，在以农村为重点的倡议背景下，更好地界定经济和政策层面的影响存在机会差距。
这项工作展示了TSBM在农村健康研究环境中的新颖映射，并探讨了将TSBM的概念和领域用作编码工具的细微差别。这项工作使该联盟深入了解了所支持的项目类型和影响，以及如何在未来的农村健康倡议中优先更多地探索转化科学的全面效益。
