Chung Timothy K, Gueldner Pete H, Kottakota Aakash K, Hangey Christian N, Lee Jason Y, Liang Nathan L, Vorp David A
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Clinical and Translational Sciences Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Sci Talks. 2025 Mar;13:100432. doi: 10.1016/j.sctalk.2025.100432. Epub 2025 Feb 11.
The number of medical images taken has continued to increase year over year for an aging population in the United States. It has been shown that patients understand their diagnoses better when shown a 2D or 3D image of their respective diseases. However, clinicians do not regularly show patients their images as it requires additional time and processing. In this experiment, we demonstrate the use of augmented reality to visualize abdominal aortic aneurysms using a previously developed artificial intelligence engine. Our group further expanded the number of cases used for training the stress prediction model to a total of 274 patients (206 used for training or ~ 5.4 million nodes, and 68 for testing or ~1.8 million nodes). Medical images undergo automated segmentation, and wall stresses are predicted on the 3D surface of aneurysms to view a heat map. The pipeline includes introducing elements into the Microsoft HoloLens 2 ecosystem to view models and additional analytics, enabling clinicians and patients to view the biomechanical status without the need for a computational or imaging expert. The proposed clinical workflow would allow a local server to process medical imaging data, generate point clouds, predict wall stresses on individual points, and create a 3D model with a colormap to view in augmented reality. The study revealed that neural networks and ensemble boosted tress models predicted the wall stresses more accurately (when compared to ground truth finite element analysis results). The approach is not limited to the HoloLens 2 ecosystem but can be used with other emerging augmented or virtual reality hardware systems.
在美国,随着人口老龄化,医学影像的拍摄数量持续逐年增加。研究表明,向患者展示其各自疾病的二维或三维图像时,他们能更好地理解自己的诊断结果。然而,临床医生并不经常向患者展示其影像,因为这需要额外的时间和处理。在本实验中,我们展示了如何使用增强现实技术,借助先前开发的人工智能引擎来可视化腹主动脉瘤。我们团队进一步将用于训练应力预测模型的病例数量增加到总共274名患者(206名用于训练,约540万个节点,68名用于测试,约180万个节点)。医学影像经过自动分割,在动脉瘤的三维表面预测壁应力以查看热图。该流程包括将元素引入Microsoft HoloLens 2生态系统以查看模型和其他分析结果,使临床医生和患者无需计算或成像专家即可查看生物力学状态。拟议的临床工作流程将允许本地服务器处理医学影像数据,生成点云,预测单个点的壁应力,并创建带有颜色映射的三维模型以在增强现实中查看。研究表明,神经网络和集成增强树模型能更准确地预测壁应力(与地面真值有限元分析结果相比)。该方法不仅限于HoloLens 2生态系统,还可与其他新兴的增强或虚拟现实硬件系统配合使用。