Yang Jian, Li Cong-Qing, Xia Jing-Xian, Zhu Wen-Jing, Wang Jing, He Wei, Wang Qing-Yuan, Wang Wen-Yan
Department of Obstetrics and Gynecology, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Department of Obstetrics and Gynecology, Fu Yang Women and Children's Hospital, Fuyang, Anhui, China.
Front Med (Lausanne). 2025 Apr 28;12:1555256. doi: 10.3389/fmed.2025.1555256. eCollection 2025.
This study aimed to evaluate the effects of transcervical resection of the septum (TCRS) on reproductive outcomes in women of reproductive age with two types of uterine septa.
In this retrospective cohort study, we evaluated the reproductive outcomes after TCRS in 87 women with an incomplete uterine septum and 35 women with a complete uterine septum. The study was conducted from January 2010 to December 2020 at the Second Affiliated Hospital of Anhui Medical University in China.
In Group A (incomplete uterine septum), TCRS markedly decreased the rates of spontaneous abortion and embryonic arrest ( < 0.001) while significantly enhancing the likelihood of term delivery ( < 0.001). Similarly, Group B (complete uterine septum) observed a substantial increase in pregnancy rates (from 43.5 to 82.6%), a significant decrease in spontaneous abortions ( < 0.05), and an improvement in term delivery rates ( < 0.001) post-surgery. The dimension of the septum in cases of Group A did not affect the outcome of adverse reproductive events. However, cesarean section rates were significantly higher in Group B than in Group A (76.5% vs. 47.7%). The optimal time to achieve pregnancy was within the first year for Group A and the 12th month for Group B after TCRS.
In patients undergoing TCRS, a notable decrease in spontaneous abortion rates was observed, alongside an increase in pregnancy and full-term birth rates. However, there was a concomitant rise in cesarean section rates. Furthermore, our findings indicate that patients with an incomplete uterine septum are more likely to conceive earlier than those with a complete uterine septum following surgery, thereby optimizing the timing for pregnancy.
本研究旨在评估经宫颈纵隔切除术（TCRS）对两种类型子宫纵隔的育龄期女性生殖结局的影响。
在这项回顾性队列研究中，我们评估了87例不完全子宫纵隔女性和35例完全子宫纵隔女性接受TCRS后的生殖结局。该研究于2010年1月至2020年12月在中国安徽医科大学第二附属医院进行。
A组（不完全子宫纵隔）中，TCRS显著降低了自然流产和胚胎停育率（<0.001），同时显著提高了足月分娩的可能性（<0.001）。同样，B组（完全子宫纵隔）术后妊娠率大幅提高（从43.5%提高到82.6%），自然流产显著减少（<0.05），足月分娩率有所改善（<0.001）。A组中纵隔的尺寸不影响不良生殖事件的结局。然而，B组的剖宫产率显著高于A组（76.5%对47.7%）。A组在TCRS后实现妊娠的最佳时间是在第一年内，B组是在第12个月。
接受TCRS的患者中，观察到自然流产率显著降低，同时妊娠率和足月出生率有所提高。然而，剖宫产率也随之上升。此外，我们的研究结果表明，不完全子宫纵隔的患者术后比完全子宫纵隔的患者更有可能更早受孕，从而优化了妊娠时机。
