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埃及血吸虫病与坦桑尼亚布贾希一个流行社区的死亡率

Schistosomiasis haematobium and the mortality occurring in an endemic community at Bujashi, Tanzania.

作者信息

Rugemalila J B, Asila J, Chimbe A

出版信息

Trop Geogr Med. 1985 Jun;37(2):114-8.

PMID:4035772
Abstract

A population of 4516 inhabitants of an area endemic for schistosomiasis haematobium at Bujashi, Tanzania, was investigated in 1983 seven years after a baseline study for a pilot control project to determine the disease mortality risk. The distribution of the 238 deaths occurring in the population, when analysed by the Mantel Haenszel test, showed similar age and sex specific mortality rates among the 2309 non-cases and 2109 cases found excreting schistosome eggs at the baseline urine examinations. Furthermore, the respective follow up 36 and 57 cases with and without urological sequelae on the baseline excretion urograms, also showed similar age adjusted mortality rates as did the 1663 and 446 metrifonate treated and untreated cases respectively. The findings suggested, therefore, that neither the disease nor its treatment affected the mortality occurring in the population.

摘要

1983年,在坦桑尼亚布贾希对4516名埃及血吸虫病流行地区的居民进行了调查,此次调查是在一项试点控制项目的基线研究七年后进行的,目的是确定疾病的死亡风险。通过Mantel Haenszel检验分析该人群中发生的238例死亡的分布情况,结果显示,在基线尿液检查中发现的2309名非病例和2109名排泄血吸虫卵的病例中,年龄和性别特异性死亡率相似。此外,在基线排泄尿路造影中分别对36例和57例有和没有泌尿系统后遗症的病例进行随访,结果显示年龄调整死亡率也相似,1663例接受敌百虫治疗的病例和446例未接受治疗的病例的年龄调整死亡率同样相似。因此,研究结果表明,疾病及其治疗均未影响该人群的死亡率。

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