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亚裔美国乳腺癌幸存者生活质量的多维度:一项基于技术的项目的影响。

Multiple dimensions of the quality of life among Asian American breast cancer survivors: The impact of a technology-based program.

作者信息

Im Eun-Ok, Chee Wonshik, Paul Sudeshna, Kim Seo Yun, Choi Mi-Young, Mao Jun J, Nguyen Giang T, Schapira Marilyn M, Ulrich Connie M, Yeo SeonAe, Deatrick Janet A, Inouye Jillian, Ma Grace, Meghani Salimah, Shin David, Bao Ting

机构信息

The University of Texas at Austin, USA.

The University of Texas at Austin, USA.

出版信息

Breast. 2025 May 8;82:104490. doi: 10.1016/j.breast.2025.104490.

Abstract

OBJECTIVE

The purpose of this study was to examine if a technology-based information and coaching/support program could improve the quality of life of Asian American breast cancer survivors and determine the factors that influenced the changes in the women's quality of life by the technology-based program.

METHODS

This was a randomized controlled trial with 199 Asian American breast cancer survivors (104 in the intervention group and 95 in the control group). Multiple instruments including the Functional Assessment of Cancer Therapy Scale-Breast Cancer (FACT-B) were used to assess background factors, disease factors, and the quality of life. The data were analyzed using intent-to-treat general linear models.

RESULTS

The FACT-B total and subscale scores of the intervention group increased from pre-test (T0) to post 3-months (T2), while those of the control group decreased. Significant interaction between time and group were found only in physical well-being (β = 0.84, p = .025) from T0 to T1 (post 1-month) and social well-being (β = 1.05, p = .006) from T0 to T2 within the mixed-effect model with AR1. The PRQ scores mediated the effect of the technology-based intervention on the Breast Cancer Subscale scores (p < .05) over one month (T0 to T1).

CONCLUSION

The technology-based program improved physical and social well-being among Asian American breast cancer survivors. Social support mediated the impact of the program on the quality of life. Future studies are needed on different dimensions of the quality of life with diverse groups of survivors. NCT02803593.

摘要

目的

本研究旨在探讨基于技术的信息与辅导/支持项目是否能改善亚裔美国乳腺癌幸存者的生活质量,并确定该基于技术的项目影响这些女性生活质量变化的因素。

方法

这是一项随机对照试验,共有199名亚裔美国乳腺癌幸存者(干预组104名,对照组95名)。使用包括癌症治疗功能评估量表-乳腺癌(FACT-B)在内的多种工具来评估背景因素、疾病因素和生活质量。数据采用意向性分析的一般线性模型进行分析。

结果

干预组的FACT-B总分及各子量表得分从预测试(T0)到3个月后(T2)有所增加,而对照组则下降。在具有AR1的混合效应模型中,仅在从T0到T1(1个月后)的身体幸福感(β = 0.84,p = 0.025)和从T0到T2的社会幸福感(β = 1.05,p = 0.006)方面发现了时间和组间的显著交互作用。PRQ得分在一个月内(T0到T1)介导了基于技术的干预对乳腺癌子量表得分的影响(p < 0.05)。

结论

基于技术的项目改善了亚裔美国乳腺癌幸存者的身体和社会幸福感。社会支持介导了该项目对生活质量的影响。未来需要针对不同幸存者群体的生活质量不同维度开展研究。NCT02803593。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c85/12139231/a2a01ef563da/gr1.jpg

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