支气管肺发育不良早产儿发生早产儿视网膜病变的危险因素。
Risk factors for retinopathy of prematurity among preterm infants with bronchopulmonary dysplasia.
作者信息
Zhang Haiyan, Jiang Yunhong, Zhang Xinkai, Su Linna, Yu Yu, Li Lili, Liu Dongyun
机构信息
Department of Pediatrics Medical Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
School of Medicine, Qingdao University, Qingdao, China.
出版信息
J Matern Fetal Neonatal Med. 2025 Dec;38(1):2497058. doi: 10.1080/14767058.2025.2497058. Epub 2025 May 13.
BACKGROUND
This study was designed to investigate the risk factors for retinopathy of prematurity (ROP) among the preterm infants with bronchopulmonary dysplasia (BPD).
METHODS
This retrospective study included 225 preterm infants with BPD who were admitted to our hospital between January 2016 and March 2022. These preterm infants were divided into ROP group and non-ROP group based on the presence of ROP. Logistic regression analysis was given to analyze the risk factors for ROP in the preterm infants with BPD. Spearman correlation analysis was performed to investigate the correlation between ROP severity and BPD.
RESULTS
Logistic regression analysis indicated that noninvasive ventilation and oxygen therapy increased the risk of ROP among preterm infants with BPD. Low gestational age and low birth weight increased the risk of ROP among preterm infants with BPD. There was a positive correlation between severity of ROP and BPD.
CONCLUSIONS
Low gestational age, low birth weight, noninvasive ventilation, oxygen therapy mask and nasal catheter were risk factors for ROP among preterm infants with BPD.
背景
本研究旨在调查支气管肺发育不良（BPD）早产儿发生早产儿视网膜病变（ROP）的危险因素。
方法
这项回顾性研究纳入了2016年1月至2022年3月期间我院收治的225例BPD早产儿。这些早产儿根据是否患有ROP分为ROP组和非ROP组。采用Logistic回归分析来分析BPD早产儿发生ROP的危险因素。进行Spearman相关性分析以研究ROP严重程度与BPD之间的相关性。
结果
Logistic回归分析表明，无创通气和氧疗增加了BPD早产儿发生ROP的风险。低胎龄和低出生体重增加了BPD早产儿发生ROP的风险。ROP严重程度与BPD之间存在正相关。
结论
低胎龄、低出生体重、无创通气、氧疗面罩和鼻导管是BPD早产儿发生ROP的危险因素。
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