Iordanova E, Dosheva I, Lulcheva F, Tsvetkova N, Dobrev K
Vutr Boles. 1985;24(2):78-82.
The objective of the present study was to obtain information about the duration of tissue hypoxia in patients with iron deficiency anemia. That fact is of importance for the determination of the duration of maintenance iron therapy. The level of 2,3-diphosphoglycerate was studied during the treatment, after the correction of anemic syndrome and after 60-day out-patient department treatment. The data obtained revealed that the level of 2,3-diphosphoglycerate was considerably elevated, as compared with the norm, before the treatment. After the active treatment and correction of anemic syndrome it was decreased, but remaining above the norm. By the 60th day of the out-patient department treatment the decrease continued and the level of 2,3-diphosphoglycerate approached the norm.
本研究的目的是获取缺铁性贫血患者组织缺氧持续时间的信息。这一事实对于确定维持性铁治疗的持续时间很重要。在治疗期间、贫血综合征纠正后以及门诊治疗60天后，对2,3-二磷酸甘油酸水平进行了研究。获得的数据显示，治疗前2,3-二磷酸甘油酸水平与正常水平相比显著升高。积极治疗和纠正贫血综合征后，其水平下降，但仍高于正常水平。到门诊治疗第60天时，该水平继续下降，2,3-二磷酸甘油酸水平接近正常水平。
