Boshnakova Ts, Tachev P, Nikolov R
Vutr Boles. 1985;24(2):88-92.
The authors describe two cases with primary systemic amyloidosis advancing with the picture of progressing cardiac insufficiency, clinically not distinguished. Electron microscopic study of myocardium was performed. The ultrastructural data indicate that the most likely source for synthesis of amyloid in myocardium, in primary systemic amyloidosis, are the active fibroblasts, established in interstitium.
作者描述了两例原发性系统性淀粉样变性病例,其病情进展为进行性心脏功能不全,临床上难以区分。对心肌进行了电子显微镜研究。超微结构数据表明,在原发性系统性淀粉样变性中,心肌中淀粉样蛋白合成最可能的来源是间质中已形成的活跃成纤维细胞。