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葡萄膜黑色素瘤的当前治疗方法

Current Treatment of Uveal Melanoma.

作者信息

Hanratty Katie, Finegan Gráinne, Rochfort Keith D, Kennedy Susan

机构信息

School of Biotechnology, Dublin City University, Collins Avenue, Glasnevin, Dublin 9, D09 V209 Dublin, Ireland.

Research Foundation, Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, D02 XK51 Dublin, Ireland.

出版信息

Cancers (Basel). 2025 Apr 23;17(9):1403. doi: 10.3390/cancers17091403.

DOI:10.3390/cancers17091403
PMID:40361330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12071000/
Abstract

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults worldwide [...].

摘要

葡萄膜黑色素瘤（UM）是全球成年人中最常见的原发性眼内恶性肿瘤[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/d6b5cf89f83f/cancers-17-01403-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/173ac47521b6/cancers-17-01403-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/d1723d7b8b48/cancers-17-01403-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/d6b5cf89f83f/cancers-17-01403-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/173ac47521b6/cancers-17-01403-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/d1723d7b8b48/cancers-17-01403-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9e/12071000/d6b5cf89f83f/cancers-17-01403-g003.jpg

相似文献

[1]
Current Treatment of Uveal Melanoma.

Cancers (Basel). 2025-4-23

[2]
Implications of LAG3 and CTLA4 immune checkpoints beyond PD-1/PD-L1 as a potential target in determining the prognosis of uveal melanoma patients.

Br J Ophthalmol. 2024-5-21

[3]
Immunotherapy for Uveal Melanoma - Current Knowledge and Perspectives.

Curr Med Chem. 2020

[4]
Immunotherapy for the Treatment of Uveal Melanoma: Current Status and Emerging Therapies.

Curr Oncol Rep. 2017-7

[5]
New immunotherapy approaches as the most effective treatment for uveal melanoma.

Crit Rev Oncol Hematol. 2024-2

[6]
In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis.

J Immunother Cancer. 2021-1

[7]
Prognostic significance of PD-1/PD-L1 expression in uveal melanoma: correlation with tumor-infiltrating lymphocytes and clinicopathological parameters.

Cancer Immunol Immunother. 2021-5

[8]
The Role of Immune Checkpoint Blockade in Uveal Melanoma.

Int J Mol Sci. 2020-1-29

[9]
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J Immunother Cancer. 2020-3

[10]
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J Immunother Cancer. 2020-11

本文引用的文献

[1]
Heterogeneity and molecular landscape of melanoma: implications for targeted therapy.

Mol Biomed. 2024-5-10

[2]
Uveal melanoma: Recent advances in immunotherapy.

World J Clin Oncol. 2024-1-24

[3]
Three-Year Overall Survival with Tebentafusp in Metastatic Uveal Melanoma.

N Engl J Med. 2023-12-14

[4]
Darovasertib, a novel treatment for metastatic uveal melanoma.

Front Pharmacol. 2023-7-28

[5]
Combining Melphalan Percutaneous Hepatic Perfusion with Ipilimumab Plus Nivolumab in Advanced Uveal Melanoma: First Safety and Efficacy Data from the Phase Ib Part of the Chopin Trial.

Cardiovasc Intervent Radiol. 2023-3

[6]
Imaging of Uveal Melanoma-Current Standard and Methods in Development.

Cancers (Basel). 2022-6-27

[7]
Genetic Basis and Molecular Mechanisms of Uveal Melanoma Metastasis: A Focus on Prognosis.

Front Oncol. 2022-4-11

[8]
Tebentafusp: First Approval.

Drugs. 2022-4

[9]
Safety and Efficacy of Ipilimumab plus Nivolumab and Sequential Selective Internal Radiation Therapy in Hepatic and Extrahepatic Metastatic Uveal Melanoma.

Cancers (Basel). 2022-2-24

[10]
A decade of checkpoint blockade immunotherapy in melanoma: understanding the molecular basis for immune sensitivity and resistance.

Nat Immunol. 2022-5

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