Lu Keyi, Zhang Xinmei, Zhao Liping, Xu Jikun, Li Jianmei
School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.
College of Biological and Pharmaceutical Engineering, Shandong University of Aeronautics, Binzhou 256600, China.
Foods. 2025 May 7;14(9):1646. doi: 10.3390/foods14091646.
Pall., a halophytic shrub native to arid and saline-alkaline ecosystems, represents a dual-purpose resource for ecological stabilization and functional food development. This review synthesizes current knowledge of its bioactive compounds and pharmacological properties, while identifying research gaps in stress-induced metabolic regulation. The plant contains diverse phytochemicals including phenolic glycosides (e.g., clovin), alkaloids (e.g., nitraramine), immunomodulatory polysaccharides, and anthocyanins, which collectively demonstrate superior antioxidant capacity (freeze-dried polysaccharides outperform Butylated Hydroxytoluene (BHT)), significant antihypertensive effects via angiotensin-converting enzyme (ACE) inhibition and nitric oxide (NO) pathway activation, and broad-spectrum antimicrobial activity against foodborne pathogens. Notably, its pectin components reduce allergen absorption by 72%, suggesting potential as hypoallergenic food additives. These findings validate traditional medicinal uses while revealing novel applications in functional foods and nutraceuticals. Despite promising preclinical results, key challenges remain in understanding compound synergies under environmental stress and translating findings to human applications. Future research should employ multi-omics approaches to elucidate stress-adaptive phytochemical biosynthesis, coupled with clinical validation and sustainable cultivation methods. As a model species for ecological and nutritional applications, offers innovative solutions for addressing both global health challenges (metabolic disorders) and environmental concerns (soil rehabilitation), positioning it at the forefront of climate-resilient agricultural innovation.
盐地碱蓬是一种原产于干旱和盐碱生态系统的盐生灌木,是生态稳定和功能性食品开发的两用资源。本综述综合了其生物活性化合物和药理特性的现有知识,同时确定了应激诱导代谢调节方面的研究空白。该植物含有多种植物化学物质,包括酚糖苷(如丁香苷)、生物碱(如硝胺)、免疫调节多糖和花青素,这些物质共同表现出卓越的抗氧化能力(冻干多糖优于丁基羟基甲苯(BHT)),通过抑制血管紧张素转换酶(ACE)和激活一氧化氮(NO)途径具有显著的降压作用,以及对食源性病原体的广谱抗菌活性。值得注意的是,其果胶成分可使过敏原吸收减少72%,表明其有作为低敏食品添加剂的潜力。这些发现证实了其传统药用价值,同时揭示了其在功能性食品和营养保健品中的新应用。尽管临床前结果很有前景,但在理解环境应激下化合物的协同作用以及将研究结果转化为人类应用方面仍存在关键挑战。未来的研究应采用多组学方法来阐明应激适应性植物化学物质的生物合成,同时进行临床验证和可持续种植方法。作为生态和营养应用的模式物种,盐地碱蓬为应对全球健康挑战(代谢紊乱)和环境问题(土壤修复)提供了创新解决方案,使其处于气候适应型农业创新的前沿。