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多模态成像方法用于MEN-1综合征相关肿瘤

Multimodal Imaging Approach to MEN-1 Syndrome-Associated Tumors.

作者信息

Carli Alice, Boffa Elisa, Bonatti Matteo, Chincarini Marco, Davì Maria Vittoria, Zamboni Giulia A

机构信息

Institute of Radiology, Department of Diagnostics and Public Health, Policlinico GB Rossi, University of Verona, 37134 Verona, Italy.

Department of Radiology, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of Paracelsus Medical University (PMU), 39100 Bolzano, Italy.

出版信息

Diagnostics (Basel). 2025 May 3;15(9):1164. doi: 10.3390/diagnostics15091164.

DOI:10.3390/diagnostics15091164
PMID:40361982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12071918/
Abstract

Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal dominant inherited syndrome characterized by a genetic predisposition for the development of specific hormone-secreting tumors. Effective diagnosis and management of MEN-1 require genetic testing, regular surveillance, and imaging follow-up to detect and monitor tumor growth or recurrence and to plan for surgical intervention. The aim of this narrative review is to provide an overview of the current imaging modalities and their role in the diagnosis and follow-up of patients affected by MEN-1, focusing on the detection and characterization of associated neoplasms. The knowledge of the most frequent MEN-1 associated neoplasms and their imaging features is crucial for an accurate diagnosis, management, and treatment.

摘要

1型多发性内分泌肿瘤（MEN-1）是一种常染色体显性遗传综合征，其特征是具有发生特定激素分泌肿瘤的遗传易感性。MEN-1的有效诊断和管理需要进行基因检测、定期监测以及影像学随访，以检测和监测肿瘤生长或复发，并为手术干预制定计划。本叙述性综述的目的是概述当前的影像学检查方法及其在MEN-1患者诊断和随访中的作用，重点关注相关肿瘤的检测和特征描述。了解最常见的与MEN-1相关的肿瘤及其影像学特征对于准确的诊断、管理和治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/f17c5b5d0059/diagnostics-15-01164-g009.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/9a94b886d0c8/diagnostics-15-01164-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/d275b0bf6dab/diagnostics-15-01164-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/3268c5551f4e/diagnostics-15-01164-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/f17c5b5d0059/diagnostics-15-01164-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/acd91305b637/diagnostics-15-01164-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/d7034cea35f1/diagnostics-15-01164-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/42d078aa7868/diagnostics-15-01164-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/b83088cc0846/diagnostics-15-01164-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/96198faa730b/diagnostics-15-01164-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/9a94b886d0c8/diagnostics-15-01164-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/d275b0bf6dab/diagnostics-15-01164-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/3268c5551f4e/diagnostics-15-01164-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a8b/12071918/f17c5b5d0059/diagnostics-15-01164-g009.jpg

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Diagnostics (Basel). 2024 Dec 25;15(1):11. doi: 10.3390/diagnostics15010011.
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Clinical Presentation, Diagnosis, and Management of Hyperinsulinemic Hypoglycemia in Adults: A Single-center Experience.成人高胰岛素血症性低血糖症的临床表现、诊断及管理：单中心经验
Endocr Metab Immune Disord Drug Targets. 2024 May 17. doi: 10.2174/0118715303322628240509094537.
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Diagnostic Performance of Magnetic Resonance Imaging for Parathyroid Localization of Primary Hyperparathyroidism: A Systematic Review.
磁共振成像对原发性甲状旁腺功能亢进症甲状旁腺定位的诊断性能：一项系统评价
Diagnostics (Basel). 2023 Dec 22;14(1):25. doi: 10.3390/diagnostics14010025.
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Expanding the clinical indications of [F]fluorocholine PET/CT in primary hyperparathyroidism: the evidence cannot be evaded.扩大[F]氟胆碱PET/CT在原发性甲状旁腺功能亢进症中的临床应用指征：证据无法回避。
Eur J Nucl Med Mol Imaging. 2024 Apr;51(5):1345-1348. doi: 10.1007/s00259-023-06573-x.
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