Nager G, Jenni R, Goebel N, Krayenbühl H P
Z Kardiol. 1985 Jul;74(7):384-8.
In 1979 the diagnosis of idiopathic enlargment of the right atrium had been made in four members of a family, living in the northeastern part of Switzerland. A 5-year follow-up study of these four patients by ECG, chest X-ray, bicycle-ergometry and echocardiography showed a variable evolution: One of the two patients with the originally largest atria, showed further massive enlargement of the right atrium, combined with tricuspid insufficiency. One presented unchanged echo findings. In the other two patients with originally smaller atria a discrepancy of the course was also observed: in one right atrial size increased considerably (with appearance of atrial flutter), in the other patient the size of the atrium remained unchanged. In both patients a pericardial effusion occurred. Subjective symptoms and physical working capacity did not change in the four patients.
1979年，瑞士东北部一个家族的四名成员被诊断为特发性右心房扩大。通过心电图、胸部X光、自行车运动试验和超声心动图对这四名患者进行的5年随访研究显示病情发展各异：最初心房最大的两名患者中，有一名右心房进一步大幅扩大，并伴有三尖瓣关闭不全。另一名患者的超声心动图结果未变。在最初心房较小的另外两名患者中，病情发展也存在差异：其中一名患者右心房大小显著增加（出现心房扑动），另一名患者心房大小保持不变。两名患者均出现心包积液。这四名患者的主观症状和身体工作能力均未改变。
