青少年的饮食习惯及其对微生物群和心理健康的影响。
Dietary Habits and Their Influence on the Microbiome and Mental Health in Adolescents.
作者信息
Sălcudean Andreea, Cîmpian Dora-Mihaela, Popovici Ramona-Amina, Forna Norina, Corodan-Comiati Diana-Mihaela, Sasu Andreea-Bianca, Cozma Melania-Maria, Bodo Cristina-Raluca, Enache Eduard-Cristian, Păcurar Mariana, Crăciun Ramona-Elena, Blidaru Alexandru, Jinga Viorel, Pașca Maria-Dorina, Lukacs Emese-Erika, Tilinca Mariana-Cornelia, Strete Elena-Gabriela, Crișan Andrada-Ioana, Osz Bianca-Eugenia, Muntean Daniela-Lucia
机构信息
Department of Ethics and Social Sciences, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, 540142 Târgu Mureş, Romania.
Department of Management and Communication in Dental Medicine, Faculty of Dental Medicine, Victor Babes University of Medicine and Pharmacy of Timisoara, 300041 Timisoara, Romania.
出版信息
Nutrients. 2025 Apr 29;17(9):1496. doi: 10.3390/nu17091496.
Adolescence represents a critical developmental stage where diet, gut microorganisms, and mental health are strongly interconnected. The current literature evidences the bidirectional role between dietary habits and psychological well-being, which is mediated by the gut-brain axis. The purpose of this review is to highlight the importance of dietary habits in adolescence period and the impact of different food choices on microbiota and secondary on mental health. Gut microbiota plays a vital role in the synthesis of neurotransmitters such as serotonin, dopamine, noradrenaline, and metabolites like short-chain fatty acids (SCFAs). The disruption in the composition of microbiota is called dysbiosis, which has been associated with a systemic inflammation state and chronic stress. They contribute to the onset of psychiatric disorders including MDD, anxiety, ADHD, and autism. Diets with a high quantity of sugar and low fiber contribute to alteration of microbiota and poor mental health. Additionally, early-life stress, antibiotic usage, and chronic inflammation may alter bacterial communities, with long-term implications for adolescents mental health. Dietary interventions, including the intake of prebiotics, probiotics, SCFAs, and micronutrients could restore microbial balance and improve psychiatric symptoms. This literature review highlights the critical role of diet and gut microbiota for adolescent mental health and emphasizes the need for integrative strategies to promote psychological resilience through microbiome regulation.
青春期是一个关键的发育阶段,饮食、肠道微生物群和心理健康在此阶段紧密相连。当前的文献证实了饮食习惯与心理健康之间的双向作用,这种作用是由肠-脑轴介导的。本综述的目的是强调青春期饮食习惯的重要性,以及不同食物选择对微生物群的影响,进而对心理健康产生的影响。肠道微生物群在血清素、多巴胺、去甲肾上腺素等神经递质以及短链脂肪酸(SCFAs)等代谢产物的合成中起着至关重要的作用。微生物群组成的破坏被称为生态失调,它与全身炎症状态和慢性应激有关。它们会导致包括重度抑郁症(MDD)、焦虑症、注意力缺陷多动障碍(ADHD)和自闭症在内的精神疾病的发作。高糖低纤维饮食会导致微生物群改变和心理健康不佳。此外,早期生活压力、抗生素使用和慢性炎症可能会改变细菌群落,对青少年心理健康产生长期影响。饮食干预,包括摄入益生元、益生菌、短链脂肪酸和微量营养素,可以恢复微生物平衡并改善精神症状。这篇文献综述强调了饮食和肠道微生物群对青少年心理健康的关键作用,并强调需要通过微生物群调节来促进心理韧性的综合策略。