Boral L I, Henry J B
Transfusion. 1977 Mar-Apr;17(2):163-8. doi: 10.1046/j.1537-2995.1977.17277151923.x.
For the year 1975, we examined 12,848 blood specimens using the type and screen as well as the crossmatch and detected 283 antibodies in 247 patients. Our screening reagent red blood cells were able to detect 96.11 per cent of these antibodies. If the antigen frequencies corresponding to those antibodies not detectable by our screening reagent red blood cells are taken into consideration. i.e., the incompatibility frequencies, the type and screen can be shown to be 99.99 per cent effective in preventing the transfusion of incompatible blood. Therefore, we believe that the type and screen may be safey substituted for the routine two-unit crossmatch in those operative procedures usually not requiring transfusions. Adoption of this approach would reduce patient charges, provide for more efficient distribution of our limited blood supplies, and allow for more effective utilization of blood-bank technologist time.
1975年,我们使用血型鉴定和筛查以及交叉配血试验检测了12848份血样,在247名患者中检测到283种抗体。我们的筛查试剂红细胞能够检测出其中96.11%的抗体。如果考虑到与我们的筛查试剂红细胞无法检测到的那些抗体相对应的抗原频率,即不相容频率,那么血型鉴定和筛查在预防输注不相容血液方面的有效性可达到99.99%。因此,我们认为在那些通常不需要输血的手术过程中,血型鉴定和筛查可以安全地替代常规的两单位交叉配血试验。采用这种方法将降低患者费用,更有效地分配我们有限的血液供应,并能更有效地利用血库技术人员的时间。