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腹部穿支血管交换(APEX)技术在延迟性腹壁下深动脉穿支(DIEP)皮瓣乳房重建穿支血管选择算法中的作用

The Role of the Abdominal Perforator Exchange (APEX) Technique in the Perforator Selection Algorithm for Delayed Deep Inferior Epigastric Perforator (DIEP) Flap Breast Reconstruction.

作者信息

Melnikov Dmitry V, Abdeeva Elina I, Ivanov Semyon I, Gombolevskiy Victor A

机构信息

Department of Plastic Surgery, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.

Department of Reconstructive and Plastic Surgery, Lancet Clinic, 105066 Moscow, Russia.

出版信息

J Clin Med. 2025 May 7;14(9):3256. doi: 10.3390/jcm14093256.

DOI:10.3390/jcm14093256
PMID:40364286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12072376/
Abstract

: The deep inferior epigastric artery perforator (DIEP) flap is currently the most widely used method for autologous breast reconstruction. Its primary advantage over the transverse rectus abdominis muscle (TRAM) flap is the reduction in donor-site morbidity, as it preserves the integrity of the abdominal muscles and motor nerves. Importantly, each patient's unique vascular anatomy requires an individualized approach to perforator selection and the surgical technique. : We aimed to minimize donor-site morbidity and refine the perforator selection strategy in delayed DIEP flap breast reconstruction using the abdominal perforator exchange (APEX) technique. : In this study, we prospectively and retrospectively analyzed the use of the APEX technique in patients undergoing delayed DIEP flap breast reconstruction between April 2020 and October 2024. All patients underwent preoperative non-contrast magnetic resonance angiography of the donor area. A total of 106 patients were enrolled and divided into two groups: 34 patients underwent reconstruction using the APEX technique, and 72 patients received standard DIEP flap breast reconstruction. : Our study demonstrated a statistically significant increase in operative time, averaging 30.5 min in the APEX group ( < 0.05). There was also a significant difference in the incidence of marginal flap necrosis between the two groups. No cases of myotomy were observed, and motor nerve transection was required in one case. : The APEX technique has been shown to be reliable when standard dissection would compromise the neuromuscular anatomy of the abdominal wall without compromising perfusion in the flap.

摘要

腹壁下动脉穿支(DIEP)皮瓣是目前自体乳房重建中应用最广泛的方法。与腹直肌肌皮瓣(TRAM皮瓣)相比,其主要优势在于供区并发症减少,因为它保留了腹部肌肉和运动神经的完整性。重要的是,每位患者独特的血管解剖结构需要采用个性化的穿支选择方法和手术技术。

我们旨在通过腹部穿支交换(APEX)技术,在延迟DIEP皮瓣乳房重建中尽量减少供区并发症,并优化穿支选择策略。

在本研究中,我们对2020年4月至2024年10月期间接受延迟DIEP皮瓣乳房重建的患者使用APEX技术的情况进行了前瞻性和回顾性分析。所有患者术前均对供区进行了非增强磁共振血管造影。共纳入106例患者,分为两组:34例患者采用APEX技术进行重建,72例患者接受标准DIEP皮瓣乳房重建。

我们的研究表明,手术时间有统计学意义的增加,APEX组平均增加30.5分钟(<0.05)。两组之间皮瓣边缘坏死的发生率也有显著差异。未观察到肌切开病例,仅1例需要切断运动神经。

当标准解剖会损害腹壁的神经肌肉解剖结构而不影响皮瓣灌注时,APEX技术已被证明是可靠的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/ca628d77f708/jcm-14-03256-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/77dfc2f32b7d/jcm-14-03256-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/f03f282b3127/jcm-14-03256-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/00315c64095e/jcm-14-03256-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/daf4145cae54/jcm-14-03256-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/ca628d77f708/jcm-14-03256-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/77dfc2f32b7d/jcm-14-03256-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/f03f282b3127/jcm-14-03256-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/00315c64095e/jcm-14-03256-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/daf4145cae54/jcm-14-03256-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d33/12072376/ca628d77f708/jcm-14-03256-g005.jpg

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Plast Reconstr Surg Glob Open. 2024 Dec 19;12(12):e6392. doi: 10.1097/GOX.0000000000006392. eCollection 2024 Dec.
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Current status of autologous breast reconstruction in Europe: how to reduce donor site morbidity.欧洲自体乳房重建的现状:如何降低供区并发症发生率
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Morbidity of the Donor Site and Complication Rates of Breast Reconstruction with Autologous Abdominal Flaps: A Systematic Review and Meta-Analysis.
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Breast J. 2022 Jun 24;2022:7857158. doi: 10.1155/2022/7857158. eCollection 2022.
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J Plast Reconstr Aesthet Surg. 2022 Mar;75(3):1108-1116. doi: 10.1016/j.bjps.2021.11.020. Epub 2021 Nov 15.
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Efficient DIEP Flap: Bilateral Breast Reconstruction in Less Than Four Hours.高效腹壁下动脉穿支皮瓣:不到四小时完成双侧乳房重建。
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