Gloria-Garza Marcela Alejandra, Reyna-Martínez Gustavo Raúl, Jiménez-Salas Zacarías, Campos-Góngora Eduardo, Kačániová Miroslava, Aguirre-Cavazos Diana Elena, Bautista-Villarreal Minerva, Leos-Rivas Catalina, Elizondo-Luevano Joel Horacio
Facultad de Odontología, Universidad Autónoma de Nuevo León, Dr. Eduardo Aguirre Pequeño S/N, Monterrey 64460, NL, Mexico.
Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N, Cd. Universitaria, San Nicolás de los Garza 66455, NL, Mexico.
Plants (Basel). 2025 May 5;14(9):1390. doi: 10.3390/plants14091390.
Dental caries remains one of the most widespread global health concerns, significantly affecting both oral and overall health. Conventional treatments typically rely on chemical-based products which, although effective, are often associated with undesirable side effects such as tooth staining, altered taste, and the development of antimicrobial resistance. As a response, plant-based natural alternatives have gained attention as promising strategies for the prevention and management of dental caries. This review highlights the antibacterial properties of medicinal plants and their potential applications in dentistry, with a particular focus on their activity against a broad range of bacteria and microorganisms involved in oral diseases. Numerous plant extracts and bioactive compounds-including polyphenols, flavonoids, and essential oils-have demonstrated antimicrobial, anti-inflammatory, and antioxidant properties that contribute to maintaining oral health. Although in vitro and in vivo studies support their therapeutic potential, clinical trials assessing long-term efficacy and safety remain scarce. Future research should prioritize the standardization of extraction methods, dosage, and formulations to facilitate the integration of these natural alternatives into conventional dental care practices.
龋齿仍然是全球最普遍的健康问题之一,对口腔健康和整体健康都有重大影响。传统治疗通常依赖于化学产品,这些产品虽然有效,但往往会带来不良副作用,如牙齿染色、味觉改变和抗菌耐药性的产生。作为应对措施,基于植物的天然替代品作为预防和治疗龋齿的有前景的策略受到了关注。这篇综述强调了药用植物的抗菌特性及其在牙科中的潜在应用,特别关注它们对多种参与口腔疾病的细菌和微生物的活性。许多植物提取物和生物活性化合物,包括多酚、黄酮类化合物和精油,都已证明具有抗菌、抗炎和抗氧化特性,有助于维持口腔健康。尽管体外和体内研究支持它们的治疗潜力,但评估长期疗效和安全性的临床试验仍然很少。未来的研究应优先考虑提取方法、剂量和配方的标准化,以促进将这些天然替代品纳入传统牙科护理实践。