Singh Manraj, Nibber Mehak, Kaur Gurjinder, Raswan Uday S, Joseph Ariana, Zaita Brittany, Singh Jake, Singh Adityabikram, Talwar Akshi, Kaur Harkanwal, Taneja Deepti, Ramzan Altaf U, Chhiber Sarabjit S
Basic Biomedical Sciences, Dayanand Medical College and Hospital, Ludhiana, IND.
Basic Biomedical Sciences, Touro College of Osteopathic Medicine, Middletown, USA.
Cureus. 2025 Apr 13;17(4):e82179. doi: 10.7759/cureus.82179. eCollection 2025 Apr.
Introduction Premature fusion of one or more cranial sutures results in a diverse set of conditions collectively known as craniosynostosis. It is primarily responsible for cosmetic issues and occasionally associated with complications like brain growth restriction, raised intracranial pressure (ICP), and blindness. Management ranges from conservative surgical procedures such as suturectomies to more extensive procedures, including frontal bone remodeling with fronto-orbital advancement (FBR with FOA) and total calvarial reconstructions (TCVR). Currently, there is no consensus on an ideal procedure for a particular type of surgery for this condition. Methods A retrospective review of 26 consecutive patients treated at a single tertiary center in India was performed. Sloan's surgical outcome class and parent satisfaction score to compare different forms of intervention. Transfusion requirements, length of hospital, and increase in head circumference post-operation were also used. Results The mean age in our cohort was 10.9 months, with a ratio of 9:4 male-to-female. The overall assessment of pre- vs. post-operative head circumference revealed a strong significant mean improvement from 42.85 cm to 44.73 cm (p<0.001). A comparison of measured variables for all 26 patients revealed a significant difference in Sloan's surgical outcomes class (5.4 vs 1.2, p<0.001), Parent satisfaction score (5.1 vs 9.1, p<0.001) and increase in head circumference (cm) post-operation (0.74 vs 2.39, p<0.001) when comparing suturectomies vs extensive procedure like FBR with FOA and TCVR. Conclusion Our results favored FBR with FOA and TCVR over simple suturectomies for more satisfactory and long-lasting results with acceptable mortality and morbidity.
一条或多条颅骨缝过早融合会导致一系列不同的病症,统称为颅缝早闭。它主要引发美容问题,偶尔还会伴有诸如脑生长受限、颅内压升高(ICP)和失明等并发症。治疗方法从诸如缝骨切除术等保守手术到更广泛的手术,包括额眶前移的额骨重塑术(FBR 联合 FOA)和全颅骨重建术(TCVR)。目前,对于这种病症的特定类型手术,尚无关于理想手术方式的共识。
对印度一家单一三级中心连续治疗的 26 例患者进行回顾性研究。采用斯隆手术结果分类和家长满意度评分来比较不同的干预形式。还使用了输血需求、住院时间和术后头围增加情况。
我们队列中的平均年龄为 10.9 个月,男女比例为 9:4。术前与术后头围的总体评估显示,平均头围从 42.85 厘米显著提高到 44.73 厘米(p<0.001)。对所有 26 例患者测量变量的比较显示,在比较缝骨切除术与 FBR 联合 FOA 和 TCVR 等广泛手术时,斯隆手术结果分类(5.4 对 1.2,p<0.001)、家长满意度评分(5.1 对 9.1,p<0.001)和术后头围增加(厘米)(0.74 对 2.39,p<0.001)存在显著差异。
我们的结果表明,与简单的缝骨切除术相比,FBR 联合 FOA 和 TCVR 能带来更令人满意和持久的效果,且死亡率和发病率可接受。