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一名有癌症病史的患者,在游走性舌炎病变上方因裁缝针创伤后出现罕见的舌部溃疡性毛细血管瘤:病例报告

An Unusual Lingual Ulcerated Capillary Angioma After Dressmaker Needle Trauma, Above Migratory Glossitis Lesion, in a Patient With a History of Cancer: A Case Report.

作者信息

Casu Cinzia, Butera Andrea, Gerosa Clara, Scribante Andrea, Murgia Martina Salvatorina, Orrù Germano

机构信息

Oral Biotechnology Laboratory (OBL), Department of Molecular Biology, University of Cagliari, Cagliari, Italy.

Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.

出版信息

Case Rep Dent. 2025 May 6;2025:9921608. doi: 10.1155/crid/9921608. eCollection 2025.

DOI:10.1155/crid/9921608
PMID:40365073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12074836/
Abstract

Vascular malformations are relatively common benign proliferative lesions of vascular and connective tissue origin that can present in oral regions, such as on the tongue. Etiological factors include genetic mutations or molecular changes related to syndromes, trauma, vascular wall resistance to blood flow, and may form part of other systemic diseases. Clinically, they can be extremely heterogeneous, and they can also cause important diagnostic doubts. Migratory glossitis is a very common oral condition in the general population, linked to immunological factors, sometimes connected with intestinal health problems. The aim of this work is to report an atypical case of ulcerated angioma on the tongue and the contemporary presence of migratory glossitis. A 54-year-old Caucasian female with a history of an intestinal cancer presented a particular exophytic lesion on the tip of the tongue where the hypothetical diagnosis of oral metastasis had been included, also for the rapid onset of the oral lesion. The dressmaker's needle trauma related to the patient's work activity could have been the triggering factor for the appearance of the neoformation. The diagnosis after histological evaluation was ulcerated capillary angioma. Due to the unusual presentation of this type of lesion, it is needed to reconsider current knowledge on the etiopathogenesis of vascular lesions and its clinical inclusion in the differential diagnosis.

摘要

血管畸形是血管和结缔组织来源的相对常见的良性增生性病变,可出现在口腔区域,如舌部。病因包括与综合征相关的基因突变或分子变化、创伤、血管壁对血流的阻力,并且可能是其他全身性疾病的一部分。临床上,它们具有极大的异质性,也会引发重要的诊断疑问。游走性舌炎在普通人群中是一种非常常见的口腔疾病,与免疫因素有关,有时与肠道健康问题相关。本文旨在报告一例舌部溃疡性血管瘤的非典型病例以及同时存在的游走性舌炎。一名有肠癌病史的54岁白种女性,舌尖出现了一个特殊的外生性病变,由于口腔病变起病迅速,曾考虑为口腔转移瘤的假设诊断。与患者工作活动相关的裁缝针创伤可能是新生物出现的触发因素。组织学评估后的诊断为溃疡性毛细血管瘤。由于这类病变的不寻常表现,有必要重新审视目前关于血管病变病因发病机制的知识以及其在鉴别诊断中的临床纳入情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12eb/12074836/3372cda929e6/CRID2025-9921608.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12eb/12074836/3b6c9eacd834/CRID2025-9921608.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12eb/12074836/3372cda929e6/CRID2025-9921608.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12eb/12074836/3b6c9eacd834/CRID2025-9921608.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12eb/12074836/3372cda929e6/CRID2025-9921608.002.jpg

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Clin Exp Dent Res. 2024 Dec;10(6):e70011. doi: 10.1002/cre2.70011.
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Cureus. 2024 May 10;16(5):e60068. doi: 10.7759/cureus.60068. eCollection 2024 May.
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Clinical Use of Paraprobiotics for Pregnant Women with Periodontitis: Randomized Clinical Trial.
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Dent J (Basel). 2024 Apr 19;12(4):116. doi: 10.3390/dj12040116.
4
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Capillary Hemangioma Managed With Laser Ablation: A Case Report.激光消融治疗毛细血管瘤:一例报告
J Lasers Med Sci. 2023 Sep 30;14:e39. doi: 10.34172/jlms.2023.39. eCollection 2023.
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Terminology and Classifications of Vascular Lesions Based on Molecular Identification.基于分子鉴定的血管病变术语和分类。
Oral Maxillofac Surg Clin North Am. 2024 Feb;36(1):35-48. doi: 10.1016/j.coms.2023.09.010.
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