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2012年至2023年期间精神卫生保健和物质使用障碍专科医疗服务中精神药物的使用情况。

Use of psychotropic medications in the specialist health service for mental health care and substance use disorders in 2012-23.

作者信息

Seljeflot Liv Marit, Blix Hege Salvesen, Andersson Yvonne, Hynnekleiv Torfinn

机构信息

Avdeling for klinisk farmasi og rådgivning, Sykehusapotekene Innlandet, Sykehusapotekene HF.

Avdeling for resistens- og infeksjonsforebygging, Folkehelseinstituttet, og, Farmasøytisk institutt, Universitetet i Oslo.

出版信息

Tidsskr Nor Laegeforen. 2025 May 12;145(6). doi: 10.4045/tidsskr.24.0531. Print 2025 May 13.

Abstract

BACKGROUND

Data on the use of psychotropic medications in specialist mental health services and interdisciplinary specialised treatment for substance use disorders (SUDs) are useful both as cross-sectional indicators and as time series data for monitoring trends. The figures can help form a basis for evaluating rational use of medications in hospitals.

MATERIAL AND METHOD

Purchasing data for anxiolytics, antidepressants, mood stabilisers and antipsychotics from the Hospital Pharmacies Drug Statistics for the period 2012-23 were used. The data are sourced from sales to specialist mental health clinics and for SUD treatment. Defined daily doses and the number of defined daily doses per 100 bed-days were used as units of measurement.

RESULTS

Use of anxiolytics increased by 127 % from 2012 to 2023, while decreasing by 24 % for antidepressants. The use of mood stabilisers and lithium decreased by 26 % and 16 %, respectively. Total use of antipsychotics increased by 29 %, while rising by 79 % for depot injections.

INTERPRETATION

Significant changes in medication use were observed during the reference period. Further studies are needed to identify the causes and effects of the changed prescribing patterns.

摘要

背景

精神科专科医疗服务中使用精神药物以及针对物质使用障碍(SUD)的跨学科专科治疗的数据,作为横断面指标和监测趋势的时间序列数据均很有用。这些数据有助于为评估医院合理用药奠定基础。

材料与方法

使用了2012年至2023年期间医院药房药物统计中的抗焦虑药、抗抑郁药、心境稳定剂和抗精神病药的采购数据。数据来源于向精神科专科诊所的销售以及用于SUD治疗的销售。限定日剂量以及每100床日的限定日剂量数用作计量单位。

结果

从2012年到2023年,抗焦虑药的使用量增加了127%,而抗抑郁药的使用量下降了24%。心境稳定剂和锂盐的使用量分别下降了26%和16%。抗精神病药的总使用量增加了29%,而长效注射剂的使用量增加了79%。

解读

在参考期内观察到用药情况有显著变化。需要进一步研究以确定处方模式改变的原因和影响。

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