在一名感染乙型肝炎病毒（HBV）的献血者中鉴定出近乎完整的细小病毒B19基因组。
Near-complete torque teno virus (TTV) genome identified in a blood donor infected with hepatitis B virus (HBV).
作者信息
Ragupathy Viswanath, Kelley Kylan, Hewlett Indira
机构信息
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
出版信息
Microbiol Resour Announc. 2025 Jun 12;14(6):e0117824. doi: 10.1128/mra.01178-24. Epub 2025 May 14.
Abstract
We have identified a near full-length torque teno virus (TTV) genome sequence in plasma from a blood donor infected with hepatitis B virus. The consensus sequence of TTV was extracted from Nanopore metagenomic sequencing. The identified TTV open reading frame 1 is 3,062 nucleotides (nt) long and shares 90%-100% identity with other human TTVs.
摘要
我们从一名感染乙型肝炎病毒的献血者血浆中鉴定出了近乎全长的细小病毒B19（TTV）基因组序列。TTV的共有序列是从纳米孔宏基因组测序中提取的。鉴定出的TTV开放阅读框1长3062个核苷酸（nt），与其他人类TTV的序列一致性为90%-100%。
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