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Potential of Berberine for Rheumatoid Arthritis Prevention and Treatment.

作者信息

Xu Hao-Jie, Su Yin

机构信息

Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, 100044, China.

Department of Rheumatology and Immunology, Peking University People's Hospital, Qingdao, Shandong Province, 266111, China.

出版信息

Chin J Integr Med. 2025 May 14. doi: 10.1007/s11655-025-4217-y.

DOI:10.1007/s11655-025-4217-y

PMID:40366564

Abstract

摘要

相似文献

Potential of Berberine for Rheumatoid Arthritis Prevention and Treatment.

Chin J Integr Med. 2025 May 14. doi: 10.1007/s11655-025-4217-y.

Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis.

Bone Joint Res. 2023 Feb;12(2):91-102. doi: 10.1302/2046-3758.122.BJR-2022-0269.R1.

Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals.

Curr Rheumatol Rev. 2021;17(1):113-121. doi: 10.2174/1573397116666200907111303.

Role of activating transcription factor 3 as a mediator of the protective effects of berberine against lipopolysaccharide-stimulated SW982 cells and in rheumatoid arthritis animal models.

Toxicol Appl Pharmacol. 2025 Apr;497:117279. doi: 10.1016/j.taap.2025.117279. Epub 2025 Feb 25.

Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential.

Pharmacol Res. 2021 Jul;169:105667. doi: 10.1016/j.phrs.2021.105667. Epub 2021 May 11.

Berberine in rheumatoid arthritis: a comprehensive review and meta-analysis of its anti-inflammatory and immunomodulatory mechanisms in animal models.

Inflammopharmacology. 2025 Jan;33(1):215-229. doi: 10.1007/s10787-024-01612-x. Epub 2024 Dec 23.

Anti-arthritic effect of berberine on adjuvant-induced rheumatoid arthritis in rats.

Biomed Pharmacother. 2017 May;89:887-893. doi: 10.1016/j.biopha.2017.02.099. Epub 2017 Mar 7.

Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes.

Exp Biol Med (Maywood). 2011 Jul;236(7):859-66. doi: 10.1258/ebm.2011.010366. Epub 2011 Jun 15.

[Berberine inhibits autophagy and promotes apoptosis of fibroblast-like synovial cells from rheumatoid arthritis patients through the ROS/mTOR signaling pathway].

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20;43(4):552-559. doi: 10.12122/j.issn.1673-4254.2023.04.07.

Immunomodulatory effects of berberine on the inflamed joint reveal new therapeutic targets for rheumatoid arthritis management.

J Cell Mol Med. 2020 Nov;24(21):12234-12245. doi: 10.1111/jcmm.15803. Epub 2020 Sep 23.

本文引用的文献

Berberine in rheumatoid arthritis: a comprehensive review and meta-analysis of its anti-inflammatory and immunomodulatory mechanisms in animal models.

Inflammopharmacology. 2025 Jan;33(1):215-229. doi: 10.1007/s10787-024-01612-x. Epub 2024 Dec 23.

Berberine ameliorates vascular dysfunction by downregulating TMAO-endoplasmic reticulum stress pathway via gut microbiota in hypertension.

Microbiol Res. 2024 Oct;287:127824. doi: 10.1016/j.micres.2024.127824. Epub 2024 Jul 20.

Exploring Cardiovascular Risk Factors and Atherosclerosis in Rheumatoid Arthritis.

Eur J Intern Med. 2024 Oct;128:1-9. doi: 10.1016/j.ejim.2024.07.016. Epub 2024 Jul 23.

Protective Effects of Berberine on Nonalcoholic Fatty Liver Disease in db/db Mice via AMPK/SIRT1 Pathway Activation.

Curr Med Sci. 2024 Oct;44(5):902-911. doi: 10.1007/s11596-024-2914-y. Epub 2024 Jul 23.

Berberine, a natural alkaloid: Advances in its pharmacological effects and mechanisms in the treatment of autoimmune diseases.

Int Immunopharmacol. 2024 Aug 20;137:112422. doi: 10.1016/j.intimp.2024.112422. Epub 2024 Jun 15.

Incidence and risk factors of major cardiovascular events in rheumatoid arthritis and psoriatic arthritis: A population-based cohort study.

Semin Arthritis Rheum. 2024 Apr;65:152416. doi: 10.1016/j.semarthrit.2024.152416. Epub 2024 Feb 15.

Anti-inflammatory, antioxidant, and immunomodulatory effects of Berberis vulgaris and its constituent berberine, experimental and clinical, a review.

Phytother Res. 2024 Apr;38(4):1882-1902. doi: 10.1002/ptr.8077. Epub 2024 Feb 15.

Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.

Chin J Integr Med. 2024 Apr;30(4):299-310. doi: 10.1007/s11655-023-3753-6. Epub 2024 Jan 12.

Berberine ameliorates collagen-induced arthritis in mice by restoring macrophage polarization via AMPK/mTORC1 pathway switching glycolytic reprogramming.

Int Immunopharmacol. 2023 Nov;124(Pt B):111024. doi: 10.1016/j.intimp.2023.111024. Epub 2023 Oct 10.

Wnt/β-catenin signaling pathway promotes abnormal activation of fibroblast-like synoviocytes and angiogenesis in rheumatoid arthritis and the intervention of Er Miao San.

Phytomedicine. 2023 Nov;120:155064. doi: 10.1016/j.phymed.2023.155064. Epub 2023 Sep 2.

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Potential of Berberine for Rheumatoid Arthritis Prevention and Treatment.

作者信息

Xu Hao-Jie, Su Yin

机构信息

Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, 100044, China.

Department of Rheumatology and Immunology, Peking University People's Hospital, Qingdao, Shandong Province, 266111, China.

出版信息

Chin J Integr Med. 2025 May 14. doi: 10.1007/s11655-025-4217-y.

DOI:10.1007/s11655-025-4217-y

PMID:40366564

Abstract

摘要

相似文献

Potential of Berberine for Rheumatoid Arthritis Prevention and Treatment.

Chin J Integr Med. 2025 May 14. doi: 10.1007/s11655-025-4217-y.

Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis.

Bone Joint Res. 2023 Feb;12(2):91-102. doi: 10.1302/2046-3758.122.BJR-2022-0269.R1.

Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals.

Curr Rheumatol Rev. 2021;17(1):113-121. doi: 10.2174/1573397116666200907111303.

Role of activating transcription factor 3 as a mediator of the protective effects of berberine against lipopolysaccharide-stimulated SW982 cells and in rheumatoid arthritis animal models.

Toxicol Appl Pharmacol. 2025 Apr;497:117279. doi: 10.1016/j.taap.2025.117279. Epub 2025 Feb 25.

Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential.

Pharmacol Res. 2021 Jul;169:105667. doi: 10.1016/j.phrs.2021.105667. Epub 2021 May 11.

Berberine in rheumatoid arthritis: a comprehensive review and meta-analysis of its anti-inflammatory and immunomodulatory mechanisms in animal models.

Inflammopharmacology. 2025 Jan;33(1):215-229. doi: 10.1007/s10787-024-01612-x. Epub 2024 Dec 23.

Anti-arthritic effect of berberine on adjuvant-induced rheumatoid arthritis in rats.

Biomed Pharmacother. 2017 May;89:887-893. doi: 10.1016/j.biopha.2017.02.099. Epub 2017 Mar 7.

Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes.

Exp Biol Med (Maywood). 2011 Jul;236(7):859-66. doi: 10.1258/ebm.2011.010366. Epub 2011 Jun 15.

[Berberine inhibits autophagy and promotes apoptosis of fibroblast-like synovial cells from rheumatoid arthritis patients through the ROS/mTOR signaling pathway].

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20;43(4):552-559. doi: 10.12122/j.issn.1673-4254.2023.04.07.

Immunomodulatory effects of berberine on the inflamed joint reveal new therapeutic targets for rheumatoid arthritis management.

J Cell Mol Med. 2020 Nov;24(21):12234-12245. doi: 10.1111/jcmm.15803. Epub 2020 Sep 23.

本文引用的文献

Berberine in rheumatoid arthritis: a comprehensive review and meta-analysis of its anti-inflammatory and immunomodulatory mechanisms in animal models.

Inflammopharmacology. 2025 Jan;33(1):215-229. doi: 10.1007/s10787-024-01612-x. Epub 2024 Dec 23.

Berberine ameliorates vascular dysfunction by downregulating TMAO-endoplasmic reticulum stress pathway via gut microbiota in hypertension.

Microbiol Res. 2024 Oct;287:127824. doi: 10.1016/j.micres.2024.127824. Epub 2024 Jul 20.

Exploring Cardiovascular Risk Factors and Atherosclerosis in Rheumatoid Arthritis.

Eur J Intern Med. 2024 Oct;128:1-9. doi: 10.1016/j.ejim.2024.07.016. Epub 2024 Jul 23.

Protective Effects of Berberine on Nonalcoholic Fatty Liver Disease in db/db Mice via AMPK/SIRT1 Pathway Activation.

Curr Med Sci. 2024 Oct;44(5):902-911. doi: 10.1007/s11596-024-2914-y. Epub 2024 Jul 23.

Berberine, a natural alkaloid: Advances in its pharmacological effects and mechanisms in the treatment of autoimmune diseases.

Int Immunopharmacol. 2024 Aug 20;137:112422. doi: 10.1016/j.intimp.2024.112422. Epub 2024 Jun 15.

Incidence and risk factors of major cardiovascular events in rheumatoid arthritis and psoriatic arthritis: A population-based cohort study.

Semin Arthritis Rheum. 2024 Apr;65:152416. doi: 10.1016/j.semarthrit.2024.152416. Epub 2024 Feb 15.

Anti-inflammatory, antioxidant, and immunomodulatory effects of Berberis vulgaris and its constituent berberine, experimental and clinical, a review.

Phytother Res. 2024 Apr;38(4):1882-1902. doi: 10.1002/ptr.8077. Epub 2024 Feb 15.

Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.

Chin J Integr Med. 2024 Apr;30(4):299-310. doi: 10.1007/s11655-023-3753-6. Epub 2024 Jan 12.

Berberine ameliorates collagen-induced arthritis in mice by restoring macrophage polarization via AMPK/mTORC1 pathway switching glycolytic reprogramming.

Int Immunopharmacol. 2023 Nov;124(Pt B):111024. doi: 10.1016/j.intimp.2023.111024. Epub 2023 Oct 10.

Wnt/β-catenin signaling pathway promotes abnormal activation of fibroblast-like synoviocytes and angiogenesis in rheumatoid arthritis and the intervention of Er Miao San.

Phytomedicine. 2023 Nov;120:155064. doi: 10.1016/j.phymed.2023.155064. Epub 2023 Sep 2.

Potential of Berberine for Rheumatoid Arthritis Prevention and Treatment.

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Potential of Berberine for Rheumatoid Arthritis Prevention and Treatment.

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