Abodunrin Olunike Rebecca, Akinsolu Folahanmi Tomiwa, Ola Oluwabukola Mary, Olagunju Mobolaji Timothy, Ferife Vivienne, Lukwa Akim Tafadzwa, Lawal Ishak Kayode, Eleje George Uchenna, Ezechi Oliver Chukwujekwu
Center for Reproduction and Population Health Studies, Nigerian Institute of Medical Research, Lagos, Nigeria.
Department of Biostatistics and Epidemiology, Nanjing Medical University, Nanjing, China.
PLOS Glob Public Health. 2025 May 14;5(5):e0004605. doi: 10.1371/journal.pgph.0004605. eCollection 2025.
HPV self-sampling has the potential to improve early detection of cervical cancer among women living with HIV (WLHIV), but its acceptability varies, creating implementation challenges, especially in sub-Saharan Africa. This study aims to assess the acceptability of HPV self-sampling among WLHIV. We searched PubMed, Web of Science, CINAHL, Academic Medical Ultimate, Cochrane databases, and Google Scholar. The review protocol was registered with PROSPERO (CRD42022299781). Inclusion criteria were based on population, intervention, comparison, and outcome. Statistical analysis was done with R Studio version 4.3.2, and data abstraction was performed in Microsoft Excel. The analysis included 14 studies on the acceptability of HPV self-sampling among WLHIV. The overall acceptability rate was 73%. The pooled data showed that 94% felt comfortable with self-sampling, 72% found it easy to use, 10% reported pain, 14% felt embarrassed, and 41% felt confident about the process. The study found that a majority of WLHIV accepted HPV self-sampling, a higher rate than in the general female population. Many participants had concerns about the method's efficacy. This indicates that while WLHIV generally views self-sampling positively, additional education and support are needed to improve their confidence in its accuracy and reliability.
人乳头瘤病毒（HPV）自我采样有潜力改善对感染艾滋病毒女性（WLHIV）宫颈癌的早期检测，但它的可接受性各不相同，这带来了实施方面的挑战，尤其是在撒哈拉以南非洲地区。本研究旨在评估WLHIV对HPV自我采样的可接受性。我们检索了PubMed、科学网、护理学与健康领域数据库、学术医学大全、考克兰数据库和谷歌学术。该综述方案已在国际前瞻性系统评价注册库（PROSPERO，注册号CRD42022299781）登记。纳入标准基于人群、干预措施、对照和结果。使用R Studio 4.3.2版本进行统计分析，并在Microsoft Excel中进行数据提取。分析纳入了14项关于WLHIV对HPV自我采样可接受性的研究。总体可接受率为73%。汇总数据显示，94%的人对自我采样感到自在，72%的人觉得其易于使用，10%的人报告有疼痛，14%的人感到尴尬，41%的人对该过程有信心。研究发现，大多数感染艾滋病毒女性接受HPV自我采样，这一比例高于一般女性人群。许多参与者担心该方法的有效性。这表明，虽然感染艾滋病毒女性总体上对自我采样持积极看法，但仍需要更多教育和支持，以增强她们对其准确性和可靠性的信心。
