尼日利亚女性人群中的高危型人乳头瘤病毒感染：一项系统评价和荟萃分析。
High-risk human papillomavirus infection among Nigerian women: A systematic review and meta-analysis.
机构信息
Nigerian Institute of Medical Research, Lagos.
Lead City University, Ibadan.
出版信息
J Int Med Res. 2023 Jul;51(7):3000605231182884. doi: 10.1177/03000605231182884.
OBJECTIVE
We conducted a systematic review and meta-analysis to determine the prevalence of high-risk human papillomavirus (hrHPV) infection and its associated risk factors among Nigerian women.
METHODS
Databases including PubMed, Web of Science, Scopus, and CINAHL were searched for studies published between 01 January 2001 and 31 December 2022, that had reported hrHPV infection and associated risk factors among women in Nigeria from ages of 25 to 65 years.
RESULTS
Of the 136 records initially retrieved, 18 were eligible for analysis. The prevalence of hrHPV genotypes was 25%, and for hrHPV 16 and 18, were 9% and 10%, respectively. The prevalence of hrHPV among HIV+ve women was 71%. The most common risk factors for hrHPV were age at coitarche and multiple sex partners.
CONCLUSION
hrHPV prevalence is high in women in Nigeria and common among those HIV+ve. Rapid screening for hrHPV genotypes is recommended, and multivalent HPV vaccines should be considered for women.
目的
我们进行了系统评价和荟萃分析，以确定尼日利亚女性中高危型人乳头瘤病毒（hrHPV）感染及其相关危险因素的流行率。
方法
检索了 PubMed、Web of Science、Scopus 和 CINAHL 等数据库，以确定在 2001 年 1 月 1 日至 2022 年 12 月 31 日期间发表的报告了尼日利亚 25 至 65 岁女性中 hrHPV 感染及其相关危险因素的研究。
结果
最初检索到的 136 篇记录中，有 18 篇符合分析条件。hrHPV 基因型的流行率为 25%，hrHPV16 和 18 的流行率分别为 9%和 10%。HIV+ve 女性中 hrHPV 的流行率为 71%。hrHPV 的最常见危险因素是初次性交年龄和多个性伴侣。
结论
尼日利亚女性中 hrHPV 的流行率较高，HIV+ve 女性中更为常见。建议对 hrHPV 基因型进行快速筛查，并应考虑为女性接种多价 HPV 疫苗。
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