Watson R J, Hooper T L, Ingram G
Age Ageing. 1985 Jul;14(4):225-9. doi: 10.1093/ageing/14.4.225.
A retrospective study was performed of 163 patients aged 65 years and over with a diagnosis of duodenal ulceration admitted to one Health District over a period of six years. Eighty per cent of the patients were admitted with acute complications, 50% bled and 30% were perforated. A large proportion of these patients were currently taking anti-inflammatory agents. Patients managed surgically for their complications had a high mortality rate but this was even higher for those managed conservatively. Giant ulcers were found to occur frequently in this age group which had a tendency to severe bleeding. It is concluded that early diagnosis and prompt surgical intervention is essential in the management of complications associated with duodenal ulceration in the elderly.
对一个健康区六年间收治的163例65岁及以上十二指肠溃疡患者进行了一项回顾性研究。80%的患者因急性并发症入院,50%有出血症状,30%发生穿孔。这些患者中很大一部分目前正在服用抗炎药。因并发症接受手术治疗的患者死亡率很高,但保守治疗的患者死亡率更高。发现这个年龄组中巨型溃疡经常发生,且有严重出血的倾向。得出的结论是,对于老年十二指肠溃疡相关并发症的处理,早期诊断和及时的手术干预至关重要。