[膀胱癌根治性膀胱切除术：95例临床病理研究]

[Total cystectomy for urinary bladder cancer: clinicopathological study of 95 cases].

作者信息

Murase T, Takashi M, Aota Y, Shimoji T, Miyake K, Mitsuya H

出版信息

Hinyokika Kiyo. 1985 Apr;31(4):615-21.

Abstract

Total cystectomy was performed on 95 patients with primary urinary bladder cancer between 1973 and 1983. Histopathological and prognostic studies were reviewed according to the general rules for clinical and pathological studies on bladder cancer. The cancer histological type were transitional cell carcinoma in 87 cases, squamous cell carcinoma in 5 cases, adenocarcinoma in 2 cases, and undifferentiated carcinoma in 1 case. The overall 5-year actuarial survival rate was 36.0%. As for the growth pattern of the bladder cancer, the 5-year survival rates for the patients with papillary non-invasive type (PNT), papillary invasive type (PIT), and non-papillary invasive type (NIT) were 100%, 25.8% and 34.8% respectively. As for the stage, the 5-year survival rates for the patients with pTa, pT1, pT2, pT3a, pT3b, and pT4 were 81.8%, 64.7%, 40.1%, 30.5%, 22.6% and 6.7% respectively. Of 87 patients with transitional cell carcinoma, the 5-year survival rates for the patients with grade 1, grade 2 and grade 3 were 100%, 43.0% and 32.1% respectively. Intramural lymphatic invasion and vascular invasion and intramural histopathological mode of spread were significant indicators of prognosis.

摘要

1973年至1983年间，对95例原发性膀胱癌患者实施了全膀胱切除术。根据膀胱癌临床和病理研究的一般规则，对组织病理学和预后研究进行了回顾。癌组织学类型为移行细胞癌87例，鳞状细胞癌5例，腺癌2例，未分化癌1例。总体5年精算生存率为36.0%。至于膀胱癌的生长方式，乳头状非浸润型（PNT）、乳头状浸润型（PIT）和非乳头状浸润型（NIT）患者的5年生存率分别为100%、25.8%和34.8%。至于分期，pTa、pT1、pT2、pT3a、pT3b和pT4患者的5年生存率分别为81.8%、64.7%、40.1%、30.5%、22.6%和6.7%。在87例移行细胞癌患者中，1级、2级和3级患者的5年生存率分别为100%、43.0%和32.1%。壁内淋巴浸润、血管浸润和壁内组织病理学扩散方式是重要的预后指标。