Needs for radionuclide metrology in the use of alpha-emitters for radionuclide-based therapy: Summary of an International Workshop.

An International Workshop on Standards and Measurements for Alpha-Emitting Radionuclides in Therapeutic Nuclear Medicine was held on 22-23 February 2024 at the Bureau International des Poids et Mesures (BIPM) and online. The workshop brought together members of the medical and metrology communities who play crucial roles in developing Targeted Alpha Therapy (TAT) radiopharmaceuticals. The workshop aimed to discuss ways to improve radioactivity measurements of alpha-emitting radionuclides for TAT. Through the presentations and discussions that took place over the two days of the workshop, information was exchanged, and recommendations for improvements that could lead to improved safety and effectiveness in TAT were proposed. This paper summarizes the topics and important ideas that were discussed at the workshop and presents recommendations for all the communities involved in the development of TAT radiopharmaceuticals to consider.