Sullivan K M, Halpin T J, Marks J S, Kim-Farley R
Am J Dis Child. 1985 Sep;139(9):909-12. doi: 10.1001/archpedi.1985.02140110063030.
An outbreak of mumps in a middle school (grades 6 through 8) in Ohio during 1981 was investigated to determine the effectiveness of mumps vaccine. Of the 481 middle school students on whom questionnaires were completed, 62 (12.4%) exhibited clinical mumps. The overall vaccine efficacy was 81.2% when children with a history of mumps disease are excluded from the analysis. Using a logistic regression model with the presence or absence of clinical mumps as the dependent variable, three factors were found to be significant: mumps vaccine, a history of mumps disease, and sex. Factors that did not significantly affect the rate of disease among vaccinated pupils included whether the mumps vaccine was administered singly or in combination with rubella and/or measles vaccine, age at vaccination, year of vaccination, and month of vaccination.
1981年，俄亥俄州一所中学（六年级至八年级）爆发了腮腺炎疫情，此次调查旨在确定腮腺炎疫苗的有效性。在完成问卷调查的481名中学生中，62人（12.4%）出现了临床腮腺炎症状。若在分析中排除有腮腺炎病史的儿童，总体疫苗效力为81.2%。以是否出现临床腮腺炎症状作为因变量，使用逻辑回归模型发现有三个因素具有显著性：腮腺炎疫苗、腮腺炎病史和性别。在接种疫苗的学生中，对疾病发生率没有显著影响的因素包括腮腺炎疫苗是单独接种还是与风疹和/或麻疹疫苗联合接种、接种年龄、接种年份和接种月份。
