Barron B A, Busin M, Page C, Bergsma D R, Kaufman H E
Am J Ophthalmol. 1985 Sep 15;100(3):377-84. doi: 10.1016/0002-9394(85)90497-0.
We compared the effects of Viscoat and Healon on postoperative increases in intraocular pressure in patients undergoing uncomplicated extracapsular cataract extraction with posterior chamber intraocular lens implantation in a prospective, randomized, single-masked study. Eleven eyes received Viscoat and 13 received Healon. The Viscoat or Healon was aspirated from the anterior chamber with the irrigation-aspiration tip of an automated irrigation-aspiration system at the end of the procedure. No prophylactic intraoperative or postoperative ocular hypotensive agents were used. Intraocular pressure was measured at three, six, 12, and 24 hours postoperatively. Compared with preoperative intraocular pressure, postoperative intraocular pressure was significantly increased in both the Viscoat group and the Healon group. Some postoperative intraocular pressures were as high as 50 to 60 mm Hg, despite removal of the viscoelastic substance at the end of surgery. There was no significant difference in the postoperative intraocular pressures of the Viscoat group and the Healon group.
在一项前瞻性、随机、单盲研究中，我们比较了Viscoat和Healon对接受无并发症囊外白内障摘除联合后房型人工晶状体植入术患者术后眼压升高的影响。11只眼使用Viscoat，13只眼使用Healon。手术结束时，用自动灌注抽吸系统的灌注抽吸头从前房中吸出Viscoat或Healon。术中及术后均未使用预防性降眼压药物。术后3小时、6小时、12小时和24小时测量眼压。与术前眼压相比，Viscoat组和Healon组术后眼压均显著升高。尽管手术结束时已去除粘弹剂，但一些患者术后眼压高达50至60毫米汞柱。Viscoat组和Healon组术后眼压无显著差异。
