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实体器官和造血细胞移植受者旅行相关感染的预防

Prevention of travel-related infections in solid organ and hematopoietic cell transplant recipients.

作者信息

Wilson Dib Rita, Henao-Cordero José, Sassine Joseph, Siegrist Emily A, Agudelo Higuita Nelson Iván

机构信息

Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd., Oklahoma City, OK 73104, USA.

Infectious Diseases Section, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

出版信息

Ther Adv Infect Dis. 2025 May 12;12:20499361251338571. doi: 10.1177/20499361251338571. eCollection 2025 Jan-Dec.

Abstract

The growing population of transplant survivors receiving a solid organ transplantation (SOT) or a hematopoietic cell transplantation (HCT) and the emergence of cellular therapies are contributing to an increase in high-risk travelers to different regions of the world. Timely pretravel evaluations are essential for risk stratification and a segway to planning proper immunization, personalized antimicrobial prophylaxis, and preventative counseling based on individual medical conditions, immune status, and potential drug-drug interactions. In addition, clinicians can provide emergency and specialized medical center contacts as available. We herein review the available strategies for the prevention and management of travel-related infections in adult recipients of HCT and SOT.

摘要

接受实体器官移植(SOT)或造血细胞移植(HCT)的移植受者人数不断增加,以及细胞疗法的出现,导致前往世界不同地区的高风险旅行者增多。旅行前及时评估对于风险分层至关重要,也是基于个体医疗状况、免疫状态和潜在药物相互作用来规划适当免疫接种、个性化抗菌预防和预防性咨询的切入点。此外,临床医生可提供可用的紧急和专业医疗中心联系方式。我们在此回顾了成人HCT和SOT受者预防和管理与旅行相关感染的可用策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4948/12075967/55fa0da47cff/10.1177_20499361251338571-fig1.jpg

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