Uslan Daniel Z, Patel Robin, Virk Abinash
Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Transplantation. 2008 Aug 15;86(3):407-12. doi: 10.1097/TP.0b013e31817c0673.
Although solid-organ transplant recipients (SOTR) have an increased risk of acquiring illnesses, they may not receive optimal pretravel care. We conducted a cross-sectional survey of travel activities and outcomes among SOTR.
Two thousand five hundred fifty-four consecutive living SOTR from Mayo Clinic were surveyed regarding travel practices, pretravel counseling, exposure risks, and illness using a previously standardized and validated questionnaire.
One thousand one hundred thirty SOTR (44%) responded to the survey and were included in the study. The most common transplanted organs were liver (519 patients) and kidney (515 patients). Three hundred and three (27%) respondents reported travel outside of the United States or Canada after their transplant. Liver recipients were more likely to travel than other organ recipients. Ninety-six percent of travelers reported that they did not seek specific pretravel healthcare before their trip. Forty-nine SOTR (16%) traveled to destinations at higher risk for infectious diseases; travelers to these destinations were more likely to be men (73% vs. 54% of low-infection risk travelers, P=0.018) or born outside the United Stated or Canada (29% vs. 6% P<0.0001). Twenty-four travelers (8%) required medical attention because of illness; illness was more likely among travelers to high-infection risk (18%) than low-risk (6%) destinations, P=0.004.
International travel was common after solid organ transplantation, although the majority traveled to destinations at low risk for infectious disease. Although generally SOTR were able to travel safely, travelers to destinations at high-risk for infection had a significant rate of illness. Pretravel counseling and interventions were infrequent and should be improved.
尽管实体器官移植受者（SOTR）患病风险增加，但他们可能未获得最佳的旅行前护理。我们对SOTR的旅行活动及结果进行了一项横断面调查。
使用先前标准化并经验证的问卷，对梅奥诊所连续2554例活体SOTR就旅行习惯、旅行前咨询、暴露风险和疾病情况进行了调查。
1130例SOTR（44%）回复了调查并纳入研究。最常见的移植器官是肝脏（519例患者）和肾脏（515例患者）。303例（27%）受访者报告在移植后前往美国或加拿大以外的地区旅行。肝脏移植受者比其他器官移植受者更有可能旅行。96%的旅行者报告在旅行前未寻求特定的旅行前医疗保健。49例SOTR（16%）前往传染病风险较高的目的地旅行；前往这些目的地的旅行者更有可能是男性（73%，而低感染风险旅行者为54%，P = 0.018）或在美国或加拿大以外出生（29%，而低感染风险旅行者为6%，P < 0.0001）。24例旅行者（8%）因疾病需要医疗护理；前往高感染风险目的地的旅行者患病的可能性（18%）高于前往低风险目的地的旅行者（6%），P = 0.004。
实体器官移植后国际旅行很常见，尽管大多数人前往传染病风险较低的目的地。虽然一般来说SOTR能够安全旅行，但前往高感染风险目的地的旅行者患病比例较高。旅行前咨询和干预很少见，应加以改进。
