Guo Changsheng, Dai Ting, Zhang Haoran, Luo Meng, Gao Jing, Feng Xiaodong
Heilongjiang University of Chinese Medicine, Harbin, China.
Rehabilitation Center, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Front Aging Neurosci. 2025 Apr 30;17:1495218. doi: 10.3389/fnagi.2025.1495218. eCollection 2025.
A systematic review and meta-analysis was conducted to validate the effects of resistance training (RT) on body composition and physical function in older females with sarcopenic obesity (SO).
Systematic review and meta-analysis.
Older females (≥60 years).
Four electronic databases-PubMed, Web of Science, Embase, and the Cochrane Library-were comprehensively searched through June 2024. Randomized controlled trials (RCTs) comparing RT with non-exercise interventions or health education were included. Outcomes measured included key indicators such as body composition and physical function. The quality of the included studies was evaluated using the Physiotherapy Evidence Database (PEDRO) score, and the risk of bias was assessed utilizing the Cochrane Risk of Bias 2.0 Tool (RoB 2). Ultimately, a meta-analysis was conducted using RevMan 5.4.
Results of our meta-analysis revealed that RT partially ameliorated body composition in patients, significantly reducing body fat percentage (BF%; WMD = -2.83, 95% CI: -4.55 to -1.12, = 0.001). However, through comparative analysis of the control groups, we revealed that it did not significantly influence other indices such as body mass index (BMI; WMD = -0.42, 95% CI: -1.92 to 1.08, = 0.58), total skeletal muscle mass (TSM; WMD = -0.62, 95% CI: -2.38 to 1.15, = 0.49), or bone mineral density (BMD; WMD = 0.01, 95% CI: -0.03 to 0.05, = 0.68). Notably, RT demonstrated substantial efficacy in enhancing physical function, as evidenced by improvements in the 10-meter walk test (10WMT; WMD = 0.22 s, 95% CI: 0.04 to 0.39, = 0.01), Timed Up and Go test (TUG; WMD = -2.23 s, 95% CI: -2.96 to -1.49, = 0.00001), and Timed Chair Rise test (TCR; WMD = 5.20 repetitions, 95% CI: 3.98 to 6.43, = 0.00001).
This meta-analysis indicates that RT exerts a significant positive influence on the physical function of older females with SO. Despite these benefits, the impact on body composition parameters, such as BF%, appears to be limited. These findings underscore the need for further investigation into the mechanisms by which RT affects body composition in this patient population.
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进行一项系统评价和荟萃分析，以验证抗阻训练（RT）对患有肌少症肥胖（SO）的老年女性身体成分和身体功能的影响。
系统评价和荟萃分析。
老年女性（≥60岁）。
全面检索了四个电子数据库——PubMed、科学网、Embase和考克兰图书馆，检索截至2024年6月的文献。纳入比较RT与非运动干预或健康教育的随机对照试验（RCT）。测量的结果包括身体成分和身体功能等关键指标。使用物理治疗证据数据库（PEDRO）评分评估纳入研究的质量，并使用考克兰偏倚风险2.0工具（RoB 2）评估偏倚风险。最终，使用RevMan 5.4进行荟萃分析。
我们的荟萃分析结果显示，RT部分改善了患者的身体成分，显著降低了体脂百分比（BF%；加权均数差[WMD]= -2.83，95%置信区间[CI]：-4.55至-1.12，P = 0.001）。然而，通过对对照组的比较分析，我们发现它对其他指标没有显著影响，如体重指数（BMI；WMD = -0.42，95% CI：-1.92至1.08，P = 0.58）、总骨骼肌质量（TSM；WMD = -0.62，95% CI：-2.38至1.15，P = 0.49）或骨密度（BMD；WMD = 0.01，95% CI：-0.03至0.05，P = 0.68）。值得注意的是，RT在增强身体功能方面显示出显著效果，10米步行试验（10WMT）有所改善（WMD = 0.22秒，95% CI：0.04至0.39，P = 0.01）、定时起立行走试验（TUG）（WMD = -2.23秒，95% CI：-2.96至-1.49，P = 0.00001）和定时椅子起立试验（TCR）（WMD = 5.20次重复，95% CI：3.98至6.43，P = 0.00001）证明了这一点。
这项荟萃分析表明，RT对患有SO的老年女性的身体功能有显著的积极影响。尽管有这些益处，但对身体成分参数（如BF%）的影响似乎有限。这些发现强调需要进一步研究RT影响该患者群体身体成分的机制。
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