Rodman Michael, Fang Diana, Khan Majid, Wu Qingqing
Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, USA.
Pathology, Johns Hopkins University School of Medicine, Baltimore, USA.
Cureus. 2025 Apr 14;17(4):e82264. doi: 10.7759/cureus.82264. eCollection 2025 Apr.
We report a case of a 75-year-old male with an incidental and indeterminate lytic lesion of the C2 vertebral body. After rapid enlargement over 16 months, persistent neck pain, and concern for underlying occult malignancy, the patient underwent lesion biopsy and simultaneous balloon kyphoplasty. Histopathological analysis revealed the surprising diagnosis of intraosseous schwannoma. Spinal Intraosseous Schwannomas (SIS) are rare benign tumors, often mimicking more sinister processes on diagnostic imaging. Fortunately, their histologic appearance is identical to schwannomas found more commonly in the soft tissues, providing diagnostic certainty to otherwise ambiguous radiologic findings. Though rare, intraosseous schwannomas remain an important benign diagnostic consideration for incidental solitary lytic bone lesions. To our knowledge, this is the second published case of kyphoplasty involving an SIS.
我们报告一例75岁男性患者，其C2椎体出现偶然发现的、性质不明的溶骨性病变。在16个月内病变迅速增大、持续存在颈部疼痛且担心存在潜在隐匿性恶性肿瘤后，该患者接受了病变活检及同期球囊后凸成形术。组织病理学分析显示诊断为骨内神经鞘瘤，令人惊讶。脊柱骨内神经鞘瘤（SIS）是罕见的良性肿瘤，在诊断性影像学检查中常表现为更具恶性特征的病变。幸运的是，其组织学表现与软组织中更常见的神经鞘瘤相同，可为原本不明确的放射学表现提供诊断依据。尽管罕见，但骨内神经鞘瘤仍是偶然发现的孤立性溶骨性骨病变重要的良性诊断考虑因素。据我们所知，这是第二例发表的涉及骨内神经鞘瘤的后凸成形术病例。
