双嘧达莫对人红细胞钠钾含量的影响。
Effects of dipyridamole on sodium and potassium content of human red blood cells.
作者信息
Vettore L, De Matteis M C, Del Conte G
出版信息
Acta Haematol. 1977 Mar;57(4):193-8. doi: 10.1159/000207881.
PMID:403724
Abstract
The effects of dipyridamole on potassium and sodium content of human red blood cells from normals or from patients with hypochromic anaemia, and of normal red cells pretreated with menadione, have been studied. Dipyridamole added to the incubation medium decreases the loss of potassium and the accumulation of sodium in all three types of red cells incubated at 37 degrees C for 24 h, either with or without calcium. The possible mechanism underlying these effects of dipyridamole is discussed.
摘要
已研究双嘧达莫对正常人或低色素性贫血患者的人红细胞以及用甲萘醌预处理的正常红细胞中钾和钠含量的影响。添加到孵育培养基中的双嘧达莫可减少在37℃下孵育24小时的所有三种类型红细胞中钾的流失和钠的积累，无论有无钙存在。讨论了双嘧达莫这些作用的潜在机制。
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