[The impact of concept of disorders of gut-brain interaction on functional gastrointestinal disorders diagnosis and treatment].

Functional gastrointestinal disorders (FGIDs) include a category of diseases with gastrointestinal symptoms as the main manifestations, in which multiple factories may affect the gastrointestinal motility, induce visceral hypersensitivity, intestinal mucosal and immune function changes, the gut microbiota changes, and influence central nervous system processing the signals from gut. In essence, the pathophysiology of FGIDs is disorders of gut-brain interaction (DGBI). The characteristics of pathophysiology determine the relative specificity of the key symptoms of each FGIDs, overlapping and transition among FGIDs. Psychological factors affect patients' symptoms and symptom perception in the all levels of gut-brain interaction. The conceptual shift from FGIDs to DGBI is conducive for clinicians to understand the symptom features and the patients' feelings on the symptoms from the pathophysiological mechanism, to make a multicomponent diagnosis and select effective and individualized treatment for patients.