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室内灰尘控制与哮喘:清洁空气过滤的安慰剂对照试验

House dust control and asthma: a placebo-control trial of cleaning air filtration.

作者信息

Bowler S D, Mitchell C A, Miles J

出版信息

Ann Allergy. 1985 Sep;55(3):498-500.

PMID:4037436
Abstract

Using a placebo-control single-blind crossover trial, we investigated the effects of dust control measures alone and combined with electrostatic and high efficiency particulate air filters in the bedrooms of patients with asthma. Of 12 young asthmatics allergic to house dust and dust mite who entered the trial, nine completed all four 2-week intervals. No statistically significant improvement in symptom scores or peak expiratory flow above that recorded during the placebo interval occurred during any treatment phase. We conclude that house dust suppression adds little to the management of otherwise well controlled young asthmatic patients.

摘要

通过一项安慰剂对照单盲交叉试验,我们研究了单独的灰尘控制措施以及与静电和高效空气过滤器相结合的措施对哮喘患者卧室的影响。在12名对屋尘和尘螨过敏的年轻哮喘患者中,9名完成了所有四个为期2周的阶段。在任何治疗阶段,症状评分或呼气峰值流速均未出现比安慰剂阶段记录的数值有统计学意义的显著改善。我们得出结论,对于其他方面控制良好的年轻哮喘患者,抑制屋尘对其治疗帮助不大。

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引用本文的文献

1
House dust mite control measures for asthma.哮喘的屋尘螨控制措施
Cochrane Database Syst Rev. 2008 Apr 16;2008(2):CD001187. doi: 10.1002/14651858.CD001187.pub3.
2
Clinical effects of allergen avoidance.
Clin Rev Allergy Immunol. 2000 Jun;18(3):397-419. doi: 10.1385/CRIAI:18:3:397.
3
House dust mite and dust control.屋尘螨与灰尘控制
Clin Rev Allergy. 1988 Spring;6(1):23-33. doi: 10.1007/BF02914979.
4
Mite biology.螨类生物学。
Clin Rev Allergy. 1990 Spring;8(1):31-49. doi: 10.1007/BF02914435.
5
Prevention of bronchial hyperreactivity in children.儿童支气管高反应性的预防
Lung. 1990;168 Suppl:249-55. doi: 10.1007/BF02718139.
6
Allergen exposure and control.过敏原暴露与控制。
Exp Appl Acarol. 1992 Nov;16(1-2):181-202. doi: 10.1007/BF01201500.