Wang Yuan, Jing Xiaohan, Zhang Feilong, Tian Di, Chen Yuting, Wu Ye, Yu Ronghui
Department of Social Medicine and Health Service Management, School of Health Management, Anhui Medical University, 81 Meishan Road, Hefei, Anhui 230032, China.
Department of Cardiovascular Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road, Hefei, Anhui 230032, China.
Alcohol Alcohol. 2025 May 14;60(4). doi: 10.1093/alcalc/agaf025.
As a serious public health problem, alcoholic cardiomyopathy (ACM) has caused a heavy burden of disease.
To summarize and deeply analyze the development trend of ACM at the global, regional, and national levels in the past 30 years, this study used the age-period-cohort model to analyze the age, period, and cohort effects of the prevalence, deaths, and disability-adjusted life years (DALYs) of ACM.
The results found that the overall time trend of ACM prevalence, deaths, and DALYs had been decreasing worldwide, but the opposite trend was observed in some countries and regions. The disease burden of male ACM patients was significantly higher than that of female patients. Moreover, the ASRs of prevalence, deaths, and DALYs for ACM were positively correlated with sociodemographic index levels. Finally, this study predicted that ACM prevalence will continue to decline over the next 10 years, while death rates and DALYs are expected to increase.
Overall, the results of this study provided an insightful, up-to-date global perspective on time trends in ACM-related disease burden, shedding light on the inadequacy of ACM prevention, control, and intervention programs at multiple levels.
酒精性心肌病（ACM）作为一个严重的公共卫生问题，已造成沉重的疾病负担。
为总结并深入分析过去30年全球、区域和国家层面ACM的发展趋势，本研究采用年龄-时期-队列模型分析ACM患病率、死亡率及伤残调整生命年（DALY）的年龄、时期和队列效应。
研究结果发现，全球范围内ACM患病率、死亡率及DALY的总体时间趋势呈下降，但在一些国家和地区观察到相反趋势。男性ACM患者的疾病负担显著高于女性患者。此外，ACM患病率、死亡率及DALY的年龄标准化率与社会人口学指数水平呈正相关。最后，本研究预测未来10年ACM患病率将继续下降，而死亡率和DALY预计将上升。
总体而言，本研究结果提供了关于ACM相关疾病负担时间趋势的深刻、最新的全球视角，揭示了多层面ACM预防、控制和干预项目的不足。
